The protozoan diseases Human African Trypanosomiasis (HAT), Chagas disease (CD), and
leishmaniases span worldwide and therefore their impact is a universal concern. The …

Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …

Background Due to the absence of transcription initiation regulation of protein coding genes
transcribed by RNA polymerase II, posttranscriptional regulation is responsible for the …

Background Chronic chagasic cardiomyopathy is a debilitating and frequently fatal outcome
of human infection with the protozoan parasite, Trypanosoma cruzi. Microarray analysis of …

Schistosoma mansoni is a parasitic worm that lives in the blood vessels of its host. We
mapped the S. mansoni tegumental outer-surface structure proteome by 1D SDS-PAGE and …

Glycolysis and glyconeogenesis play crucial roles in the ATP supply and synthesis of
glycoconjugates, important for the viability and virulence, respectively, of the human …

Abstract The kinetoplastids Leishmania major, Trypanosoma brucei and Trypanosoma cruzi
are causative agents of a diverse spectrum of human diseases: leishmaniasis, sleeping …

Certain kinetoplastid (Leishmania spp. and Trypanosoma cruzi) and apicomplexan
parasites (Plasmodium falciparum and Toxoplasma gondii) are capable of invading human …

The first proteomic analysis of Trypanosoma cruzi resistance to Benznidazole (BZ) is
presented. The differential proteome of T. cruzi with selected in vivo resistance to …

Host cell invasion is an essential step during infection by Toxoplasma gondii, an intracellular
protozoan that causes the severe opportunistic disease toxoplasmosis in humans. Recent …