The significance of Cathepsin B in mediating radiation resistance in colon carcinoma cell line (Caco-2)

RF Abdelaziz, AM Hussein, MH Kotob, C Weiss… - International Journal of …, 2023 - mdpi.com
Cathepsins (Caths) are lysosomal proteases that participate in various physiological and
pathological processes. Accumulating evidence suggests that caths play a multifaceted role …

Novel Selective and Low-Toxic Inhibitor of LmCPB2.8ΔCTE (CPB) One Important Cysteine Protease for Leishmania Virulence

VP Moreira, MF da Silva Mela, LR Anjos, LF Saraiva… - Biomolecules, 2022 - mdpi.com
Leishmaniasis is a highly prevalent, yet neglected disease caused by protozoan parasites of
the genus Leishmania. In the search for newer, safer, and more effective antileishmanial …

Enhancement of Radiation Sensitivity by Cathepsin L Suppression in Colon Carcinoma Cells

RF Abdelaziz, AM Hussein, MH Kotob, C Weiss… - International Journal of …, 2023 - mdpi.com
Cancer is one of the main causes of death globally. Radiotherapy/Radiation therapy (RT) is
one of the most common and effective cancer treatments. RT utilizes high-energy radiation …

Genome analysis of Cephalotrichum gorgonifer and identification of the biosynthetic pathway for rasfonin, an inhibitor of KRAS dependent cancer

A Schüller, L Studt-Reinhold, H Berger… - Fungal Biology and …, 2023 - Springer
Background Fungi are important sources for bioactive compounds that find their applications
in many important sectors like in the pharma-, food-or agricultural industries. In an …

Genome analysis and elucidation of the biosynthetic pathway for the cRAS inhibitor rasfonin in Cephalotrichum gorgonifer

A Schüller, L Studt-Reinhold, H Berger, L Silvestrini… - 2022 - researchsquare.com
Background Fungi are important sources for bioactive compounds that find their applications
in many important sectors like in the pharma-, food-or agricultural industries. In an …