Dopamine: functions, signaling, and association with neurological diseases

MO Klein, DS Battagello, AR Cardoso… - Cellular and molecular …, 2019 - Springer
The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …

Immunomodulatory effects mediated by dopamine

R Arreola, S Alvarez-Herrera… - Journal of …, 2016 - Wiley Online Library
Dopamine (DA), a neurotransmitter in the central nervous system (CNS), has modulatory
functions at the systemic level. The peripheral and central nervous systems have …

Substantial production of dopamine in the human gastrointestinal tract

G Eisenhofer, A Åneman, P Friberg… - The Journal of …, 1997 - academic.oup.com
Considerable urinary excretion of dopamine metabolites indicates that large amounts of
dopamine are produced in unknown locations of the body. This study assessed the …

Clinical implications of enteric and central D2 receptor blockade by antidopaminergic gastrointestinal prokinetics

M Tonini, L Cipollina, E Poluzzi… - Alimentary …, 2004 - Wiley Online Library
Antidopaminergic gastrointestinal prokinetics (bromopride, clebopride, domperidone,
levosulpiride and metoclopramide) have been exploited clinically for the management of …

Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders

R Juza, K Musilek, E Mezeiova… - Medicinal Research …, 2023 - Wiley Online Library
Dopamine is a biologically active amine synthesized in the central and peripheral nervous
system. This biogenic monoamine acts by activating five types of dopamine receptors (D1 …

Cardiovascular, renal, and endocrine actions of dopamine in neonates and children

I Seri - The Journal of pediatrics, 1995 - jpeds.com
Dopamine has been widely used in pediatric and neonatal intensive care for the treatment of
hypotension or oliguria in sick preterm 1-6 and term neonates 2, 7 and in children, s …

Renal dopamine receptor function in hypertension

T Hussain, MF Lokhandwala - Hypertension, 1998 - Am Heart Assoc
Dopamine plays an important role in the regulation of renal sodium excretion. The synthesis
of dopamine and the presence of dopamine receptor subtypes (D1A, D1B as D1-like and …

Dopamine receptors in brain and periphery

P Seeman, D Grigoriadis - Neurochemistry international, 1987 - Elsevier
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Prokinetic agents for lower gastrointestinal motility disorders

WE Longo, AM Vernava III - Diseases of the colon & rectum, 1993 - journals.lww.com
Prokinetic agents are currently being investigated as potential therapies for motility disorders
of the lower gastrointestinal tract. Cholinergic agonists such as bethanechol are known to …

The neurobiology of stress ulcers

GB Glavin, R Murison, JB Overmier, WP Pare… - Brain Research …, 1991 - Elsevier
We have reviewed the neurobiology of stress ulcers from animal models to potential
pharmacotherapeutic mechanisms. The evidence strongly supports the hypothesis that …