The assessment of percutaneous permeation of molecules is a key step in the evaluation of
dermal or transdermal delivery systems. If the drugs are intended for delivery to humans, the …

Poly (lactic-co-glycolic acid)(PLGA) microspheres are a sustained-release drug delivery
system with several successful commercial products used for the treatment of a variety of …

The skin barrier function has been attributed to the stratum corneum and represents a major
challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a …

In the present study, in vitro permeation experiments in a Franz diffusion cell were performed
using different synthetic polymeric membranes and pig ear skin to evaluate a rivastigmine …

In vitro–in vivo correlation (IVIVC) is a predictive mathematical model describing the
relationship between an in vitro property and a relevant in vivo response of drug products …

The objective of the present study was to fabricate microneedles for delivering lipophilic
active ingredients (APIs) using digital light processing (DLP) printing technology and quality …

Cannabidiol, a non-psychoactive constituent of cannabis, has garnered much attention after
United States Food and Drug Administration approved Epidiolex® for oral use. Although …

Lipid-based formulations (LBFs) have demonstrated a great potential in enhancing the oral
absorption of poorly water-soluble drugs. However, construction of in vitro and in vivo …

Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …

Bioavailability assessment in the development phase of a drug product is vital to reveal the
disadvantageous properties of the substance and the possible technological interventions …