ABSTRACT The Gram-negative bacterium Vibrio cholerae is responsible for the severe
diarrheal pandemic disease cholera, representing a major global public health concern …

Gram-negative enteropathogenic bacteria use a variety of strategies to cause disease in the
human host and gene regulation in some form is typically a part of the strategy. This article …

To be successful pathogens, bacteria must often restrict the expression of virulence genes to
host environments. This requires a physical or chemical marker of the host environment as …

ToxR, a Vibrio cholerae transmembrane one-component signal transduction factor, lies
within a regulatory cascade that results in the expression of ToxT, toxin coregulated pilus …

Vibrio parahaemolyticus is the leading cause of seafood-borne gastroenteritis in humans
worldwide. The major virulence factor responsible for the enteropathogenicity of this …

The virulence regulator ToxR initiates and coordinates gene expression needed by Vibrio
cholerae to colonize the small intestine and cause disease. Despite its prominence in V …

The speciation of Salmonella occurred by acquisition of genomic islands from other bacterial
species and continued to diverge into subspecies and serovars with diferent range of host …

ToxR facilitates TcpP-mediated activation of the toxT promoter in Vibrio cholerae, initiating a
regulatory cascade that culminates in cholera toxin secretion and toxin coregulated pilus …

Two of the primary virulence regulators of V ibrio cholerae, ToxR and TcpP, function together
with cognate effector proteins. ToxR undergoes regulated intramembrane proteolysis (RIP) …

Vibrio cholerae (V. cholerae) is an aquatic bacterium responsible for acute and fatal cholera
outbreaks worldwide. When V. cholerae is ingested, the bacteria colonize the epithelium of …