Cardiovascular effects of stimulant and non-stimulant medication for children and adolescents with ADHD: a systematic review and meta-analysis of trials of …

L Hennissen, MJ Bakker, T Banaschewski, S Carucci… - CNS drugs, 2017 - Springer
Background Many children and adolescents with attention deficit/hyperactivity disorder
(ADHD) are treated with stimulant and non-stimulant medication. ADHD medication may be …

Cardiometabolic effects of psychotropic medications

O Abosi, S Lopes, S Schmitz… - … molecular biology and …, 2018 - degruyter.com
Background Many psychiatric disorders including schizophrenia, bipolar disorder and major
depression convey an excess burden of cardiovascular morbidity and mortality. The …

Decreased dopamine brain reactivity in marijuana abusers is associated with negative emotionality and addiction severity

ND Volkow, GJ Wang, F Telang… - Proceedings of the …, 2014 - National Acad Sciences
Moves to legalize marijuana highlight the urgency to investigate effects of chronic marijuana
in the human brain. Here, we challenged 48 participants (24 controls and 24 marijuana …

Exercise impact on sustained attention of ADHD children, methylphenidate effects

JA Medina, TLB Netto, M Muszkat, AC Medina… - ADHD Attention Deficit …, 2010 - Springer
Attention deficit hyperactivity disorder (ADHD) is related to a deficiency of central
catecholamines (CA) in cognitive, biochemical, and physical tests, and pharmaceutical …

Cerebral blood flow predicts differential neurotransmitter activity

J Dukart, Š Holiga, C Chatham, P Hawkins, A Forsyth… - Scientific reports, 2018 - nature.com
Application of metabolic magnetic resonance imaging measures such as cerebral blood flow
in translational medicine is limited by the unknown link of observed alterations to specific …

[HTML][HTML] Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis

HJ Zhu, KS Patrick, HJ Yuan, JS Wang… - The American Journal of …, 2008 - cell.com
The human carboxylesterase 1 (CES1) gene encodes for the enzyme carboxylesterase 1, a
serine esterase governing both metabolic deactivation and activation of numerous …

Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination

CM Hysek, LD Simmler, N Schillinger… - International journal …, 2014 - academic.oup.com
Abstract Methylphenidate and 3, 4-methylenedioxymethamphetamine (MDMA,'ecstasy') are
widely misused psychoactive drugs. Methylphenidate increases brain dopamine and …

The effect of methylphenidate and atomoxetine on heart rate and systolic blood pressure in young people and adults with attention-deficit hyperactivity disorder …

EF Liang, SZ Lim, WW Tam, CS Ho, MW Zhang… - International journal of …, 2018 - mdpi.com
Objectives: This meta-analysis aims to study the effects of atomoxetine and methylphenidate
on heart rate (HR), systolic blood pressure (SBP), and a number of adverse cardiac events …

The hedonic response to cigarette smoking is proportional to dopamine release in the human striatum as measured by positron emission tomography and [11C] …

SP Barrett, I Boileau, J Okker, RO Pihl, A Dagher - Synapse, 2004 - Wiley Online Library
Positron emission tomography and [11C] raclopride were used to assess the dopaminergic
response to cigarette smoking in ten smokers. Nicotine‐deprived smokers were scanned …

Risk of serious cardiovascular problems with medications for attention-deficit hyperactivity disorder

J Martinez-Raga, C Knecht, N Szerman, MI Martinez - CNS drugs, 2013 - Springer
Attention-deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder
characterized by persistent symptoms of inattention, hyperactivity and/or impulsivity. The …