Cirrhosis-associated immune dysfunction

A Albillos, R Martin-Mateos, S Van der Merwe… - Nature Reviews …, 2022 - nature.com
The term cirrhosis-associated immune dysfunction (CAID) comprises the distinctive
spectrum of immune alterations associated with the course of end-stage liver disease …

[PDF][PDF] The value of liver and spleen stiffness for evaluation of portal hypertension in compensated cirrhosis

T Reiberger - Hepatology communications, 2022 - Wiley Online Library
Patients with compensated advanced chronic liver disease who develop clinically significant
portal hypertension (CSPH) are at high risk for hepatic decompensation and mortality if left …

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update

CPG Panel, A Berzigotti, E Tsochatzis, J Boursier… - Journal of …, 2021 - Elsevier
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

AASLD practice guidance on risk stratification and management of portal hypertension and varices in cirrhosis

DE Kaplan, C Ripoll, M Thiele, BE Fortune… - Hepatology, 2024 - journals.lww.com
This Practice Guidance from the American Association for the Study of Liver Disease
(AASLD) intends to coalesce best practice recommendations for the identification of portal …

[HTML][HTML] Predicting portal thrombosis in cirrhosis: a prospective study of clinical, ultrasonographic and hemostatic factors

F Turon, EG Driever, A Baiges, E Cerda… - Journal of …, 2021 - Elsevier
Background & Aims Portal vein thrombosis (PVT) is a relatively frequent event in patients
with cirrhosis. While different risk factors for PVT have been reported, such as decreased …

[PDF][PDF] Changes in hepatic venous pressure gradient predict hepatic decompensation in patients who achieved sustained virologic response to interferon‐free therapy

M Mandorfer, K Kozbial, P Schwabl, D Chromy… - …, 2020 - Wiley Online Library
Background and Aims Sustained virologic response (SVR) to interferon (IFN)‐free therapies
ameliorates portal hypertension (PH); however, it remains unclear whether a decrease in …

Coagulation in liver disease: a guide for the clinician

PG Northup, SH Caldwell - Clinical Gastroenterology and Hepatology, 2013 - Elsevier
The human hemostasis system is complex and poorly understood after decades of intense
scientific study. Despite multiple defects in routine coagulation laboratory studies in patients …

[HTML][HTML] The sequential application of Baveno VII criteria and VITRO score improves diagnosis of clinically significant portal hypertension

M Jachs, L Hartl, B Simbrunner, D Bauer… - Clinical …, 2023 - Elsevier
Background & Aims Baveno VII proposed liver stiffness measurement (LSM)/platelet count
(PLT)-based criteria ('ruled out,'LSM≤ 15 kPa plus PLT≥ 150 G/L;'ruled in': LSM≥ 25 kPa) …

De novoportal vein thrombosis in virus-related cirrhosis: predictive factors and long-term outcomes

H Maruyama, H Okugawa, M Takahashi… - Official journal of the …, 2013 - journals.lww.com
OBJECTIVES: The objective of this study is to investigate predictive factors and long-term
outcomes ofde novoportal vein thrombosis (PVT) in cirrhosis. METHODS: The incidence and …

[PDF][PDF] Acute kidney injury in decompensated cirrhosis is associated with both hypo‐coagulable and hyper‐coagulable features

A Zanetto, HM Rinder, E Campello, G Saggiorato… - …, 2020 - Wiley Online Library
Background and Aims Recent evidence suggests that acute kidney injury (AKI) is the main
predictor of postparacentesis bleeding in patients with cirrhosis. To assess the factors …