Immune checkpoint inhibitor-associated pneumonitis in non-small cell lung cancer: current understanding in characteristics, diagnosis, and management

Q Zhang, L Tang, Y Zhou, W He, W Li - Frontiers in immunology, 2021 - frontiersin.org
Immunotherapy that includes programmed cell death-1 (PD-1), programmed cell death-
ligand 1 (PD-L1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibitors has …

[HTML][HTML] Chronic obstructive pulmonary disease (COPD) and lung cancer: common pathways for pathogenesis

BA Parris, HE O'Farrell, KM Fong… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) and lung cancer comprise the leading
causes of lung disease-related mortality worldwide. Exposure to tobacco smoke is a mutual …

Characteristics, incidence, and risk factors of immune checkpoint inhibitor-related pneumonitis in patients with non-small cell lung cancer

JY Cho, J Kim, JS Lee, YJ Kim, SH Kim, YJ Lee… - Lung Cancer, 2018 - Elsevier
Abstract Objectives Immune checkpoint inhibitors (ICIs) can cause pneumonitis in lung
cancer patients. We aimed to identify the clinical and radiologic characteristics, incidence …

[HTML][HTML] Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC

J Kargl, X Zhu, H Zhang, GHY Yang, TJ Friesen… - JCI insight, 2019 - ncbi.nlm.nih.gov
Immune checkpoint inhibitor (ICI) treatment has recently become a first-line therapy for many
non–small cell lung cancer (NSCLC) patients. Unfortunately, most NSCLC patients are …

Lipopolysaccharide-mediated chronic inflammation promotes tobacco carcinogen–induced lung cancer and determines the efficacy of immunotherapy

CH Liu, Z Chen, K Chen, FT Liao, CE Chung, X Liu… - Cancer Research, 2021 - AACR
Chronic obstructive pulmonary disease (COPD) is an inflammatory disease that is
associated with increased risk of lung cancer. Pseudomonas aeruginosa (PA) infections are …

Insights into lung cancer immune-based biology, prevention, and treatment

S Saab, H Zalzale, Z Rahal, Y Khalifeh… - Frontiers in …, 2020 - frontiersin.org
Lung cancer is the number one cause of cancer-related deaths. The malignancy is
characterized by dismal prognosis and poor clinical outcome mostly due to advanced-stage …

[HTML][HTML] The mechanism and risk factors for immune checkpoint inhibitor pneumonitis in non-small cell lung cancer patients

X Zhai, J Zhang, Y Tian, J Li, W Jing… - Cancer Biology & …, 2020 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are new and promising therapeutic agents for non-small
cell lung cancer (NSCLC). However, along with demonstrating remarkable efficacy, ICIs can …

Adverse effects of anti-PD-1/PD-L1 therapy in non-small cell lung cancer

C Su, H Wang, Y Liu, Q Guo, L Zhang, J Li… - Frontiers in …, 2020 - frontiersin.org
Currently, immunotherapy has shown great efficacy in clinical trials, and monoclonal
antibodies directed against immune checkpoint PD-1/PD-L1 have shown encouraging …

From COPD to lung cancer: mechanisms linking, diagnosis, treatment, and prognosis

C Qi, SW Sun, XZ Xiong - International journal of chronic …, 2022 - Taylor & Francis
Many studies have proved that the pathogenesis of the chronic obstructive pulmonary
disease (COPD) and lung cancer is related, and may cause and affect each other to a …

B cells and tertiary lymphoid structures influence survival in lung cancer patients with resectable tumors

J Tang, D Ramis-Cabrer, V Curull, X Wang… - Cancers, 2020 - mdpi.com
Simple Summary Nowadays, humans still die of lung cancer (LC), a disease mainly related
to cigarette smoking (CS). Smokers also develop chronic bronchitis, namely chronic …