Humans are unique indiscriminate carotenoid accumulators, so the human body
accumulates a wide range of dietary carotenoids of different types and to varying …

Background Age‐related macular degeneration (AMD) is a degenerative condition of the
back of the eye that occurs in people over the age of 50 years. Antioxidants may prevent …

Purpose To determine whether oral micronutrient supplementation slows geographic
atrophy (GA) progression in age-related macular degeneration (AMD). Design Post hoc …

Purpose: Age-related macular degeneration (AMD) is a neurodegenerative ophthalmic
disease. The purpose of this systematic review (SR) and meta-analysis was to evaluate if …

Given the expanding elderly population in the United States and the world, it is important to
understand the processes underlying both natural and pathological age-related changes in …

Lutein, zeaxanthin, and meso-zeaxanthin are three xanthophyll carotenoid pigments that
selectively concentrate in the center of the retina. Humans cannot synthesize lutein and …

Lipofuscin accumulates with age as intracellular fluorescent granules originating from
incomplete lysosomal digestion of phagocytosed and autophagocytosed material. The …

There is a significant and growing body of evidence that Mediterranean diet and plant-based
diets–those that maximize fruits, vegetables, legumes, whole grains and nuts; and that …

Normal tension glaucoma (NTG) is defined as a subtype of primary open-angle glaucoma
(POAG) in which the intraocular pressure (IOP) values are constantly within the statistically …

Purpose Quantification of retinal xanthophyll carotenoids in eyes with and without age-
related macular degeneration (AMD) via macular pigment optical volume (MPOV), a metric …