The Ebola virus (EBOV) is still highly infectious and causes severe hemorrhagic fevers in
primates. However, there are no regulatorily approved drugs against the Ebola virus disease …

The disease-free existence of humans is constantly under attack by a variety of infections
caused by a variety of organisms including bacteria. Notable among the bacteria is …

Diabetes is a severe chronic disease that affects 422 million adults worldwide in 2014. It was
the fifth leading cause of mortality in the Philippines in 2019. The primary cause of death of …

Various studies have established that molecules specific for MDMX inhibition or optimized
for dual inhibition of p53-MDM2/MDMX interaction signaling are more suitable for activating …

Transcription factor p53, also known as tumor suppressor protein. Encoded by the TP53
gene, the guardian of genome p53 regulates many gene pathways. Nevertheless, the …

The modulation of certain molecular targets via small-molecule ligands has been regarded
as a promising approach for the treatment and management of diabetes-related …

Purpose Beyond the pains of pregnancy, miscarriages and other child-bearing risks
associated with the pride of motherhood, Uterine fibroids (UFs) are another significant …

Acute myeloid leukemia (AML) takes center stage as a highly prevalent and aggressive
clonal disorder affecting hematological stem cells. FMS-like tyrosine kinase 3 (FLT3) …

Melanoma presents increasing prevalence and poor outcomes. Progression to aggressive
stages is characterized by overexpression of the transcription factor E2F1 and activation of …

Beyond the pains of pregnancy, miscarriages and other child-bearing risks associated with
the pride of motherhood, Uterine broids (UFs) are another signi cant reproductive age …