An ever‐increasing number of functional RNAs require a mechanistic understanding. RNA
function relies on changes in its structure, so‐called dynamics. To reveal dynamic processes …

Owing to the unique physical properties of a fluorine atom, incorporating fluoro-modifications
into nucleic acids offers striking biophysical and biochemical features, and thus significantly …

Ligand-based fluorine NMR screening has gained popularity in drug discovery projects
during the past decade and has become a powerful methodology to produce high quality …

The synthetic neomycin‐sensing riboswitch interacts with its cognate ligand neomycin as
well as with the related antibiotics ribostamycin and paromomycin. Binding of these …

The fluorine-19 nucleus was recognized early to harbor exceptional properties for NMR
spectroscopy. With 100% natural abundance, a high gyromagnetic ratio (83% sensitivity …

Spectroscopic and biophysical methods for structural determination at atomic resolution are
fundamental in studies of biological function. Here we introduce an approach to measure …

Glycan‐protein interactions play an important role in a broad range of physiological
processes, raising interest to elucidate the structural interplay. Yet, their dynamic nature …

Fluorine labeling of ribonucleic acids (RNA) in conjunction with 19F NMR spectroscopy has
emerged as a powerful strategy for spectroscopic analysis of RNA structure and dynamics …

We report here the in‐cell NMR‐spectroscopic observation of the binding of the cognate
ligand 2′‐deoxyguanosine to the aptamer domain of the bacterial 2′‐deoxyguanosine …

Nuclear magnetic resonance (NMR) spectroscopy is uniquely suited to study the dynamics
of biomolecules in solution. Most NMR studies exploit the spins of proton, carbon and …