Unveiling the multifaceted role of toll-like receptors in immunity of aquatic animals: pioneering strategies for disease management

MU Ghani, J Chen, Z Khosravi, Q Wu, Y Liu… - Frontiers in …, 2024 - frontiersin.org
The pattern recognition receptor (PRR), which drives innate immunity, shields the host
against invasive pathogens. Fish and other aquatic species with poorly developed adaptive …

Toll-like receptor evolution: does temperature matter?

C Sousa, SA Fernandes, JCR Cardoso… - Frontiers in …, 2022 - frontiersin.org
Toll-like receptors (TLRs) recognize conserved pathogen-associated molecular patterns
(PAMPs) and are an ancient and well-conserved group of pattern recognition receptors …

Nile tilapia TLR3 recruits MyD88 and TRIF as adaptors and is involved in the NF-κB pathway in the immune response

F Gao, J Pang, M Lu, Z Liu, M Wang, X Ke, M Yi… - International Journal of …, 2022 - Elsevier
TLR3 plays a crucial role in innate immunity. In the present study, OnTLR3 was identified in
the Nile tilapia Oreochromis niloticus, with a conserved LRR domain and a C-terminal TIR …

Characterization and expression analysis of the interferon regulatory factor (IRF) gene family in zig-zag eel (Mastacembelus armatus) against Aeromonas veronii …

C Han, W Huang, S Peng, J Zhou, H Zhan, W Li… - Developmental & …, 2023 - Elsevier
Interferon regulatory factors (IRFs) play an important role in innate and adaptive immune
system. However, in teleosts, the data on IRFs is still scarce. Here, for the first time, we …

Innate immunity

RA Dalmo, J Bøgwald - Principles of Fish Immunology: From Cells and …, 2022 - Springer
Research on the innate immunity has accelerated over the last decades. The main reason
for this has been the discovery of receptors recognizing danger molecules from pathogens …

Grass carp (Ctenopharyngodon idella) Mex3B positively regulates innate immunity by promoting the K63-linked ubiquitination of TLR3

J Hu, Y Xiang, X Zhu, C Hu, X Xu, D Li, Z Deng… - Fish & Shellfish …, 2023 - Elsevier
As a member of Mex3 (muscle excess protein-3) family, Mex3B (Mex-3 RNA binding family
member B) is crucial in cell proliferation and migration in mammals. In this study, an ortholog …

Toll-like receptor 3 in the hybrid yellow catfish (Pelteobagrus fulvidraco♀× p. vachelli♂): Protein structure, evolution and immune response to exogenous Aeromonas …

S Guo, M Zeng, W Gao, F Li, X Wei, Q Shi, Z Wen… - Animals, 2023 - mdpi.com
Simple Summary Yellow catfish is an economically important fish that lives in the middle and
upper reaches of the Yangtze River and the Pearl River Basin in China. Due to the intensive …

Transcriptome analysis of the spleen provides insight into the immunoregulation of Mastacembelus armatus under Aeromonas veronii infection

C Han, Q Li, Q Chen, G Zhou, J Huang… - Fish & Shellfish …, 2019 - Elsevier
Mastacembelus armatus, also known as the zigzag eel, is an economically important
species of freshwater fish that is very popular with consumers as a high-grade table fish in …

Characterization, expression and function analysis of the TLR3 gene in golden pompano (Trachinotus ovatus)

M Wu, KC Zhu, HY Guo, L Guo, B Liu, SG Jiang… - Developmental & …, 2021 - Elsevier
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) that are important in
invertebrate innate immunity for the recognition and elimination of pathogens. Although they …

Gene duplication and adaptive evolution of toll-like receptor genes in birds

J Yang, M Zhou, Y Zhong, L Xu, C Zeng, X Zhao… - Developmental & …, 2021 - Elsevier
Toll-like receptors (TLRs) play an important role in innate immune through recognizes
pathogens. In order to reveal the evolutionary patterns and adaptive evolution of avian …