Nanoscale extracellular vesicles (EVs), consisting of exomers, exosomes and microvesicles/
ectosomes, have been extensively investigated in the last 20 years, although their biological …

The first steps of vision take place in the ciliary outer segment compartment of photoreceptor
cells. The protein composition of outer segments is uniquely suited to perform this function …

The release of extracellular vesicles is observed across numerous cell types and serves a
range of biological functions including intercellular communication and waste disposal. One …

Photoreceptor cells in the vertebrate retina have a highly compartmentalized morphology for
efficient phototransduction and vision. Rhodopsin, the visual pigment in rod photoreceptors …

Organelles such as mitochondria, lysosomes, peroxisomes, and the endoplasmic reticulum
form highly dynamic cellular networks and exchange information through sites of physical …

In humans, inositol polyphosphate-5-phosphatase e (INPP5E) mutations cause retinal
degeneration as part of Joubert and MORM syndromes and can also cause non-syndromic …

Rapidly expanding research activity on extracellular vesicles (EV) holds promise for new
biomedical applications in many tissues of our body. EVs are also emerging players in the …

Rod photoreceptor neurons in the retina detect scotopic light by packaging large quantities
of the visual pigment protein rhodopsin (Rho) into stacked membrane discs within their outer …

The first steps in vision take place in photoreceptor cells, which are highly
compartmentalized neurons exhibiting significant structural variation across species. The …

Photoreceptor cells in the vertebrate retina have a highly compartmentalized morphology for
efficient long-term phototransduction. Rhodopsin, the visual pigment in rod photoreceptors …