Nanotechnology offers new solutions for the development of cancer therapeutics that display
improved efficacy and safety. Although several nanotherapeutics have received clinical …

Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …

Matrix metalloproteinases (MMPs) are major extracellular enzymes involved in cancer
initiation, progression, and metastasis. MMPs are widely used as cancer biomarkers and …

In this review we put the spotlight on crosslinked polymer nanogels, a promising platform
that has the characteristics of an “ideal” drug delivery vehicle. Some of the key aspects of …

Recent developments in nanotechnology have brought new approaches to cancer
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …

One of the main goals of nanomedicine is to develop a nanocarrier that can selectively
deliver anticancer drugs to the targeted tumors. Extensive efforts have resulted in several …

Polysaccharides contain different functional groups (such as hydroxyl, amino, carboxylic
acid, aldehydes) that make them ideal for conjugation. They are biodegradable …

Purpose Methotrexate (MTX) is one of the most widely studied and effective therapeutics
agents available to treat many solid tumors, hematologic malignancies, and autoimmune …

Peptides are attracting increasing attention as therapeutic agents, as the technologies for
peptide development and manufacture continue to mature. Concurrently, with booming …

In this extensive review, we elucidate the importance of proteases and their role in drug
development in various diseases with an emphasis on cancer. First, key proteases are …