The therapeutic effects and mechanisms of quercetin on metabolic diseases: pharmacological data and clinical evidence

H Yi, H Peng, X Wu, X Xu, T Kuang… - Oxidative medicine …, 2021 - Wiley Online Library
Metabolic diseases have become major public health issues worldwide. Searching for
effective drugs for treating metabolic diseases from natural compounds has attracted …

Research progress in the modification of quercetin leading to anticancer agents

A Massi, O Bortolini, D Ragno, T Bernardi, G Sacchetti… - Molecules, 2017 - mdpi.com
The flavonoid quercetin (3, 3′, 4′, 5, 7-pentahydroxyflavone) is widely distributed in
plants, foods, and beverages. This polyphenol compound exhibits varied biological actions …

Molecular targets of natural compounds with anti-cancer properties

M Kubczak, A Szustka, M Rogalińska - International Journal of Molecular …, 2021 - mdpi.com
Cancer is the second leading cause of death in humans. Despite rapid developments in
diagnostic methods and therapies, metastasis and resistance to administrated drugs are the …

Inhibitory effect of polyphenols from the whole green jackfruit flour against α-glucosidase, α-amylase, aldose reductase and glycation at multiple stages and their …

T Maradesha, SM Patil, KA Al-Mutairi, R Ramu… - Molecules, 2022 - mdpi.com
For the first time, α-glucosidase, α-amylase, aldose reductase, and glycation at multiple
stages inhibitory assays were used to explore the antidiabetic potential of whole unripe …

Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

Gastroprotective effects of polyphenols against various gastro-intestinal disorders: a mini-review with special focus on clinical evidence

HF Chiu, K Venkatakrishnan, O Golovinskaia… - Molecules, 2021 - mdpi.com
Polyphenols are classified as an organic chemical with phenolic units that display an array
of biological functions. However, polyphenols have very low bioavailability and stability …

Molecular docking analysis and evaluation of the antimicrobial properties of the constituents of Geranium wallichianum D. Don ex Sweet from Kashmir Himalaya

WR Mir, BA Bhat, MA Rather, S Muzamil… - Scientific reports, 2022 - nature.com
Geranium wallichianum D. Don ex Sweet is a well-known medicinal plant in Kashmir
Himalya. The evidence for its modern medicinal applications remains majorly unexplored …

LC‐HRMS Profiling and Antidiabetic, Antioxidant, and Antibacterial Activities of Acacia catechu (Lf) Willd

B Aryal, B Adhikari, N Aryal… - BioMed research …, 2021 - Wiley Online Library
Acacia catechu (Lf) Willd is a profoundly used traditional medicinal plant in Asia. Previous
studies conducted in this plant are more confined to extract level. Even though bioassay …

Universal masking during COVID-19 pandemic: Can textile engineering help public health? Narrative review of the evidence

S Beesoon, N Behary, A Perwuelz - Preventive medicine, 2020 - Elsevier
Abstract The Coronavirus Disease-2019 (COVID-19) pandemic caused by the virus SARS-
CoV-2 is spreading very quickly around the world. In less than 7 months since it became …

[HTML][HTML] In silico molecular docking and ADME/T analysis of Quercetin compound with its evaluation of broad-spectrum therapeutic potential against particular …

MM Hasan, Z Khan, MS Chowdhury, MA Khan… - Informatics in Medicine …, 2022 - Elsevier
Progression in computational research has made it possible for the in silico methods to offer
epochal benefits to both regulatory needs and the pharmaceutical industry to assess the …