Realising the full potential of data-enabled trials in the UK: a call for action

MR Sydes, Y Barbachano, L Bowman, T Denwood… - BMJ open, 2021 - bmjopen.bmj.com
Rationale Clinical trials are the gold standard for testing interventions. COVID-19 has further
raised their public profile and emphasised the need to deliver better, faster, more efficient …

Use of routine healthcare data in randomised implementation trials: a methodological mixed-methods systematic review

CX Xie, L Sun, E Ingram, A De Simoni, S Eldridge… - Implementation …, 2023 - Springer
Background Routine data are increasingly used in randomised controlled trials evaluating
healthcare interventions. They can aid participant identification, outcome assessment, and …

Personal exposure to air pollution and respiratory health of COPD patients in London

D Evangelopoulos, L Chatzidiakou… - European …, 2021 - Eur Respiratory Soc
Previous studies have investigated the effects of air pollution on chronic obstructive
pulmonary disease (COPD) patients using either fixed-site measurements or a limited …

Association between Inhaled β2-agonists Initiation and Risk of Major Adverse Cardiovascular Events: A Population-based Nested Case-Control Study

JE Amegadzie, JM Gamble, J Farrell… - International Journal of …, 2022 - Taylor & Francis
Purpose Despite ample evidence underpinning the efficacy of β2-agonists in asthma and
chronic obstructive pulmonary disease (COPD), the occurrence of β1-and β2-adrenoceptors …

Resilience and health-related quality of life in patients with pulmonary diseases receiving ambulatory oxygen therapy

S Isokääntä, K Honkalampi, H Kokki, H Sintonen… - BMC Pulmonary …, 2021 - Springer
Background Pulmonary diseases affect health-related quality of life (HRQoL), but there are
few data on patients' adaptation to a serious illness. This study assessed resilience and its …

Public and patient perspectives on the use of clinical and administrative health data to identify and contact people at risk of future illness—The case of chronic kidney …

DJ Willison, DM Nash, SE Bota, S Almadhoun… - Plos one, 2024 - journals.plos.org
For decades, researchers have used linkable administrative health data for evaluating the
health care system, subject to local privacy legislation. In Ontario, Canada, the relevant …

Feasibility of using Clinical Practice Research Datalink data to identify patients with chronic obstructive pulmonary disease to enrol into real‐world trials

G Requena, A Wolf, R Williams… - … and Drug Safety, 2021 - Wiley Online Library
Purpose To assess the feasibility of using Clinical Practice Research Datalink (CPRD) data
for identifying populations of patients with chronic obstructive pulmonary disease (COPD) …

Risk of all-cause mortality or hospitalization for pneumonia associated with inhaled β2-agonists in patients with asthma, COPD or asthma-COPD overlap

JE Amegadzie, JM Gamble, J Farrell, Z Gao - Respiratory Research, 2022 - Springer
Abstract β2-agonists provide necessary bronchodilatory action, are recommended by
existing clinical practice guidelines and are widely prescribed for patients with these …

Early detection of COPD patients' symptoms with personal environmental sensors: a remote sensing framework using probabilistic latent component analysis with …

Ş Kolozali, L Chatzidiakou, R Jones, JK Quint… - Neural Computing and …, 2023 - Springer
In this study, we present a cohort study involving 106 COPD patients using portable
environmental sensor nodes with attached air pollution sensors and activity-related sensors …

[PDF][PDF] Resilience in serious illnesses and surgeries: recovery abilities and associated conditions

S Isokääntä - 2022 - erepo.uef.fi
Resilience is the capacity to overcome stress or adversity such as serious illnesses,
traumas, or surgeries. It is based on an individual's psychological resources but is …