Click chemistry and radiochemistry: an update
The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …
Development of [18F]AmBF3 Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [18F]AmBF3-PEG7-Tyr3-Octreotide in an AR42J …
S Otaru, A Paulus, S Imlimthan, I Kuurne… - Bioconjugate …, 2022 - ACS Publications
Radiolabeled peptides have emerged as highly specific agents for targeting receptors
expressed in tumors for therapeutic and diagnostic purposes. Peptides developed for …
expressed in tumors for therapeutic and diagnostic purposes. Peptides developed for …
[HTML][HTML] Tetrazine–trans-cyclooctene ligation: Unveiling the chemistry and applications within the human body
EG Tomarchio, R Turnaturi, E Saccullo, V Patamia… - Bioorganic …, 2024 - Elsevier
Bioorthogonal reactions have revolutionized chemical biology by enabling selective
chemical transformations within living organisms and cells. This review comprehensively …
chemical transformations within living organisms and cells. This review comprehensively …
[HTML][HTML] Next generation fibroblast activation protein (FAP) targeting PET tracers-The tetrazine ligation allows an easy and convenient way to 18F-labeled (4 …
CBM Poulie, V Shalgunov, F Elvas… - European Journal of …, 2023 - Elsevier
Small-molecular fibroblast activation protein inhibitor (FAPI)-based tracer have been shown
to be promising Positron Emission Tomography (PET) 68 Ga-labeled radiopharmaceuticals …
to be promising Positron Emission Tomography (PET) 68 Ga-labeled radiopharmaceuticals …
A practical guide to automating fluorine-18 PET radiochemistry using commercially available cassette-based platforms
C Barnes, M Nair, EO Aboagye, SJ Archibald… - Reaction Chemistry & …, 2022 - pubs.rsc.org
The automation of positron emission tomography (PET) radiochemistry using cassette-
based automated radiosynthesis platforms is an essential component of clinical translation …
based automated radiosynthesis platforms is an essential component of clinical translation …
[HTML][HTML] Hetero-Diels–Alder and CuAAC Click Reactions for Fluorine-18 Labeling of Peptides: Automation and Comparative Study of the Two Methods
T Maujean, SM Ramanoudjame, S Riché, C Le Guen… - Molecules, 2024 - mdpi.com
Radiolabeled peptides are valuable tools for diagnosis or therapies; they are often
radiofluorinated using an indirect approach based on an F-18 prosthetic group. Herein, we …
radiofluorinated using an indirect approach based on an F-18 prosthetic group. Herein, we …
Automating the production of [Fe18FF2(BnMe2-tacn)] and investigating radiostabilisers for use with high-activity [18F]F−
MS Woodward, DE Runacres, J Grigg… - Pure and Applied …, 2024 - degruyter.com
The manual radiofluorination and purification of [FeF3 (BnMe2-tacn)](tacn= 1, 4, 7-
triazacyclononane) using 18F− in aqueous EtOH has been translated to a GE FASTLab™ …
triazacyclononane) using 18F− in aqueous EtOH has been translated to a GE FASTLab™ …
Automated sulfur-[18 F] fluoride exchange radiolabelling of a prostate specific membrane antigen (PSMA) targeted ligand using the GE FASTlab™ cassette-based …
Z Yang, C Barnes, J Domarkas… - Reaction Chemistry & …, 2023 - pubs.rsc.org
Sulfur-[18F] fluoride exchange radiochemistry is a rapid and convenient method for
incorporating fluorine-18 into biologically active molecules. We report a fully automated …
incorporating fluorine-18 into biologically active molecules. We report a fully automated …
Positron Emission Tomography Probes for Imaging Cytotoxic Immune Cells
A Amgheib, R Fu, EO Aboagye - Pharmaceutics, 2022 - mdpi.com
Non-invasive positron emission tomography (PET) imaging of immune cells is a powerful
approach for monitoring the dynamics of immune cells in response to immunotherapy …
approach for monitoring the dynamics of immune cells in response to immunotherapy …
[PDF][PDF] Positron Emission Tomography Probes for Imaging Cytotoxic Immune Cells. Pharmaceutics 2022, 14, 2040
A Amgheib, R Fu, EO Aboagye - 2022 - pdfs.semanticscholar.org
Non-invasive positron emission tomography (PET) imaging of immune cells is a powerful
approach for monitoring the dynamics of immune cells in response to immunotherapy …
approach for monitoring the dynamics of immune cells in response to immunotherapy …