Drying is a commonly used technique for improving the product stability of biotherapeutics.
Typically, drying is accomplished through freeze-drying, as evidenced by the availability of …

Formulation of biopharmaceuticals for pulmonary delivery is faced with the challenge of
producing particles with the optimal properties for deep lung deposition without altering the …

Innovations in biotechnology and recombinant techniques have led to a large increase in
the number of macromolecule drugs developed over the last several years. These …

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8/1987 10/1987 12/1988 3/1989 3/1989 4/1989 7/1989 8/1989 9/1989 11/1989* 5/1991 …

Improved aerodynamically light particles for delivery to the pulmonary system, and methods
for their preparation and administration are provided. In a preferred embodiment, the …

The present invention encompasses a solid dose delivery vehicle for ballistic administration
of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being …

D189, 076 3,337,740 3,407.203 3,518,340 3,622,053 3,669,113 3,823,816 3,823,843
3,856,142 3,906,950 3,921,637 3,976,773 3,980,074 3,998,226 4,013,075 4,018,619 …

The present invention encompasses a solid dose delivery vehicle for ballistic administration
of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being …

The answer to this question is simple: spray-drying is an effective, efficient means of
producing peptide/protein-loaded powders suitable for pulmonary delivery. In addition, fine …

Appl. No.: 09/891,131 Improved porous particles for drug delivery to the pulmo 1-1. nary
System, and methods for their Synthesis and adminis (22) Filed: Jun. 25, 2001 tration are …