Intrinsically disordered protein regions exist in a collection of dynamic interconverting
conformations that lack a stable 3D structure. These regions are structurally heterogeneous …

Solution-phase hydrogen/deuterium exchange (HDX) coupled to mass spectrometry (MS) is
a widespread tool for structural analysis across academia and the biopharmaceutical …

Sharing structural and mechanistic properties with the dinitrogen‐fixing enzyme
nitrogenase, d ark‐operative p rotochlorophyllide o xido r eductase (DPOR) participates in …

Enzymes that catalyze long-range electron transfer reactions are often structurally evolved to
possess two symmetrical halves. The functional advantages and mechanistic principles for …

Iron (Fe) is an essential element across the domains of life. Proteins bind Fe and
significantly influence its reactivity. The two proteins discussed in this dissertation …

Dark‐operative protochlorophyllide oxidoreductase (DPOR) is a nitrogenase‐like enzyme
that catalyzes the stereospecific two‐electron reduction of protochlorophyllide (Pchlide) to …