Approaches to test the neurotoxicity of environmental contaminants in the zebrafish model: From behavior to molecular mechanisms

JA Fitzgerald, S Könemann… - Environmental …, 2021 - Wiley Online Library
The occurrence of neuroactive chemicals in the aquatic environment is on the rise and
poses a potential threat to aquatic biota of currently unpredictable outcome. In particular …

Zebrafish as potential model for developmental neurotoxicity testing: a mini review

C De Esch, R Slieker, A Wolterbeek… - Neurotoxicology and …, 2012 - Elsevier
The zebrafish is a powerful toxicity model; biochemical assays can be combined with
observations at a structural and functional level within one individual. This mini review …

SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome

ND Shaw, H Brand, ZA Kupchinsky, H Bengani… - Nature …, 2017 - nature.com
Arhinia, or absence of the nose, is a rare malformation of unknown etiology that is often
accompanied by ocular and reproductive defects. Sequencing of 40 people with arhinia …

Reversal and relapse of hypogonadotropic hypogonadism: resilience and fragility of the reproductive neuroendocrine system

VF Sidhoum, YM Chan, MF Lippincott… - The Journal of …, 2014 - academic.oup.com
Context: A subset of patients diagnosed with idiopathic hypogonadotropic hypogonadism
(IHH) later achieves activation of their hypothalamic-pituitary-gonadal axis with …

Making senses: development of vertebrate cranial placodes

G Schlosser - International review of cell and molecular biology, 2010 - Elsevier
Cranial placodes (which include the adenohypophyseal, olfactory, lens, otic, lateral line,
profundal/trigeminal, and epibranchial placodes) give rise to many sense organs and …

[图书][B] Epigenetics: How environment shapes our genes

RC Francis - 2011 - books.google.com
Goodbye, genetic blueprint.... The first book for general readers on the game-changing field
of epigenetics. The burgeoning new science of epigenetics offers a cornucopia of insights …

Discovering genes essential to the hypothalamic regulation of human reproduction using a human disease model: adjusting to life in the “-omics” era

MI Stamou, KH Cox, WF Crowley Jr - Endocrine reviews, 2015 - academic.oup.com
The neuroendocrine regulation of reproduction is an intricate process requiring the exquisite
coordination of an assortment of cellular networks, all converging on the GnRH neurons …

Nasal placode development, GnRH neuronal migration and Kallmann syndrome

HJ Cho, Y Shan, NC Whittington… - Frontiers in Cell and …, 2019 - frontiersin.org
The development of Gonadotropin releasing hormone-1 (GnRH) neurons is important for a
functional reproduction system in vertebrates. Disruption of GnRH results in hypogonadism …

Zebrafish: an integrative system for neurogenomics and neurosciences

S Rinkwitz, P Mourrain, TS Becker - Progress in neurobiology, 2011 - Elsevier
Rapid technological advances over the past decade have moved us closer to a high
throughput molecular approach to neurobiology, where we see the merging of …

Pituitary remodeling throughout life: are resident stem cells involved?

E Laporte, A Vennekens, H Vankelecom - Frontiers in endocrinology, 2021 - frontiersin.org
The pituitary gland has the primordial ability to dynamically adapt its cell composition to
changing hormonal needs of the organism throughout life. During the first weeks after birth …