An appropriate control over cell cycle progression depends on many factors. Cyclin-
dependent kinase (CDK) inhibitor p21 (also known as p21 WAF1/Cip1) is one of these …

Despite colorectal cancer remaining a leading worldwide cause of cancer-related death,
there remains a paucity of effective treatments for advanced disease. The molecular …

The biological functions of long non‑coding RNAs (lncRNAs) in cancer have not been fully
elucidated. The present study demonstrated that the expression of a newly identified …

Iron (Fe) has become an important target for the development of anti-cancer therapeutics
with a number of Fe chelators entering human clinical trials for advanced and resistant …

Prostate cancer (PCa) is the most commonly diagnosed non-cutaneous cancer in men in the
western world. Mutations in tumor suppressor genes and in oncogenes are important for …

Simple Summary Ecotropic viral integration site 1 (EVI1) is transcriptionally activated in a
subset of myeloid leukemias. Since its discovery, other isoforms of EVI1 have been …

Abstract Background The transcription factor Ecotropic Virus Integration site 1 (EVI1)
regulates cellular proliferation, differentiation, and apoptosis, and its overexpression …

Human ectopic viral integration site 1 (EVI1) is an oncogenic transcription factor known to
play a critical role in many aggressive forms of cancer. Its selective modulation is thought to …

Background: HNSCC is the sixth most common cancer in humans and has still a very poor
prognosis. The treatment methods so far are very often associated with mutilation and …

Some colorectal cancer patients have experienced normal epithelial transformation into
inflammatory and tumor states, but the molecular basis still needs to be further determined …