Prostate cancer and the cell cycle: focusing on the role of microRNAs

IM Elazab, OA El-Feky, EG Khedr, NE El-Ashmawy - Gene, 2024 - Elsevier
Prostate cancer is the most frequent solid tumor in terms of incidence and ranks second only
to lung cancer in terms of cancer mortality among men. It has a considerably high mortality …

circGFRA1: a circular RNA with important roles in human carcinogenesis

S Khalilian, Z Mohajer, MAK Tabari… - … -Research and Practice, 2023 - Elsevier
Circular RNAs (circRNAs) are a type of covalently closed RNA molecules, which are mainly
formed by back splicing of a precursor mRNA upstream exon into a downstream exon …

Integration of miRNA expression analysis of purified leukocytes and whole blood reveals blood-borne candidate biomarkers for lung cancer

G Hong, Y Huo, Y Gao, L Ma, S Li, T Tian, H Zhong… - Epigenetics, 2024 - Taylor & Francis
Changes in leukocyte populations may confound the disease-associated miRNA signals in
the blood of cancer patients. We aimed to develop a method to detect differentially …

The important role of miR-770 as a novel potential diagnostic and therapeutic target for human cancer and other diseases

S Khalilian, SZH Imani, SA Hosseini… - Pathology-Research and …, 2023 - Elsevier
Abstract MicroRNA-770 (miR-770) is an RNA gene, located on chromosome 14q32. 2. It has
important effects on the pathobiology of cancers and other human diseases. It is known to be …

Alterations of miRNA expression in diffuse hyperplastic perilobar nephroblastomatosis: Mapping the way to understanding wilms' tumor development and differential …

Á Csók, T Micsik, Z Magyar, T Tornóczky… - International Journal of …, 2023 - mdpi.com
Wilms' tumor (WT) is the most common renal malignancy in children. In diffuse hyperplastic
perilobar nephroblastomatosis (DHPLN), nephrogenic rests result in a bulky enlargement of …

[HTML][HTML] Exploring non-coding genetic variability in ACE2: Functional annotation and in vitro validation of regulatory variants

A Giovannetti, S Lazzari, M Mangoni, A Traversa… - Gene, 2024 - Elsevier
The surge in human whole-genome sequencing data has facilitated the study of non-coding
region variations, yet understanding their biological significance remains a challenge. We …

MicroRNA Expression Profiling—Potential Molecular Discrimination of Papillary Thyroid Carcinoma Subtypes

H Silaghi, LA Pop, CE Georgescu, D Muntean… - Biomedicines, 2024 - mdpi.com
Recent research has revealed the importance of miRNAs in the diagnosis and clinical
evolution of papillary thyroid cancer (PTC). We aim to identify a specific miRNA profile that …

Review on Molecular Mechanism of Hypertensive Nephropathy

Z Peng, Q Xu, W Hu, Y Cheng - Current Pharmaceutical Design, 2023 - benthamdirect.com
Hypertension, a prevalent chronic ailment, has the potential to impair kidney function, and
thereby resulting in hypertensive nephropathy. The escalating incidence of hypertensive …

Discovery and functional characterization of LncRNAs associated with inflammation and macrophage activation

A Chini, P Guha, A Rishi, M Obaid, SMN Udden… - Methods, 2024 - Elsevier
Long noncoding RNAs (lncRNA) are emerging players in regulation of gene expression and
cell signaling and their dysregulation has been implicated in a multitude of human diseases …

MicroRNA as Biomarkers in Small Animal Gastrointestinal Inflammation and Cancer

JGH Lyngby, LN Nielsen - … in Small Animal …, 2024 - advancesinsmallanimalcare.com
Chronic gastrointestinal (GI) diseases are common in dogs and cats [1–3]. The underlying
etiology includes a wide range of conditions, from endoparasites to chronic inflammatory …