Limitations associated with conventional bone substitutes such as autografts, increasing
demand for bone grafts, and growing elderly population worldwide necessitate development …

Hydrogels have been extensively used as scaffolds in tissue engineering for cell adhesion,
proliferation, migration, and differentiation because of their high-water content and …

Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …

Advances in additive manufacturing have led to diverse patient‐specific implant designs
utilizing computed tomography, but this requires intensive work and financial implications …

Large bone defects are a major global health concern. Bone tissue engineering (BTE) is the
most promising alternative to avoid the drawbacks of autograft and allograft bone …

The issue of spine-related disorders is a global healthcare concern that requires effective
solutions to restore normal spine functioning. Spinal fusion implants have become a …

Critical-sized bone defects and articular cartilage injuries resulting from trauma,
osteonecrosis, or age-related degeneration can be often non-healed by physiological …

Titanium (Ti) implants have been widely used for the treatment of tooth loss due to their
excellent biocompatibility and mechanical properties. However, modifying the biological …

Repairing extensive bone defects that cannot self-heal has been a clinical challenge. The
construction of scaffolds with osteogenic activity through tissue engineering can provide an …

An overview on the design of nitric oxide (NO) delivering surfaces for biomedical purposes is
provided, with a focus on the advances of the past 5 years. A localized supply of NO is of a …