Perspectives of benzimidazole derivatives as anticancer agents in the new era

S Yadav, B Narasimhan - Anti-Cancer Agents in Medicinal …, 2016 - ingentaconnect.com
Cancer is one of the deadliest diseases nowadays and is a great topic for research as the
challenging task is to develop new entities with selectivity towards cancerous cells …

Aminoazole-based diversity-oriented synthesis of heterocycles

MV Murlykina, AD Morozova, IM Zviagin… - Frontiers in …, 2018 - frontiersin.org
The comprehensive review contains the analysis of literature data concerning reactions of
heterocyclization of aminoazoles and demonstrates the application of these types of …

Pyrimido[1,2-a]benzimidazoles: synthesis and perspective of their pharmacological use

VV Fedotov, VL Rusinov, EN Ulomsky… - Chemistry of …, 2021 - Springer
Pyrimido[1,2-a]benzimidazoles: synthesis and perspective of their pharmacological use |
SpringerLink Skip to main content Advertisement SpringerLink Log in Menu Find a journal …

Benzimidazole ring system as a privileged template for anticancer agents

A Kanwal, FA Saddique, S Aslam, M Ahmad… - Pharmaceutical …, 2018 - Springer
Cancer still remains a continued threat for human race in the 21st century. It is the major
cause of human casualties globally and is thus, a hot topic of research in medicinal …

4H-Chromenes as 1,3-bielectrophiles in the reaction with 2-aminobenzimidazole: synthesis of pyrimido[1,2-a]benzimidazoles

VА Osyanin, DV Osipov, KS Korzhenko… - Chemistry of …, 2021 - Springer
A method for the preparation of pyrimido [1, 2-a] benzimidazoles containing a 2-
hydroxybenzyl or (2-hydroxynaphthalen-1-yl) methyl group at position 3 was proposed …

Review on the discovery of new benzimidazole derivatives as anticancer agents: synthesis and structure-activity relationship (2010-2022)

K Shabana, Salahuddin, A Mazumder… - Letters in Drug …, 2024 - benthamdirect.com
Background: Benzimidazole (Benz-fused bicyclic ring system) is the most versatile class of
heterocyclic compounds due to its numerous applications in industrial and synthetic organic …

White-light-emitting diode (LED)-promoted one-pot synthesis of 1, 2-dihydropyrimido [1, 2-a] benzimidazoles in the presence of a new spiky magnetic nanocatalyst …

GK Kharmawlong, B Chettri, R Rymbai… - Catalysis Science & …, 2024 - pubs.rsc.org
Spiky Ni-nanoparticles were successfully synthesized and characterized using different
analytical techniques, including Fourier transform infrared spectroscopy (FT-IR), field …

Solvent-free synthesis of imidazo [1, 2-a] pyrimidine-3-carbonitriles and 1, 2, 4-triazolo [4, 3-a] pyrimidines under the catalytic performance of TiO2-[bip]-NH2+ C (NO2) …

LN Nasirmahale, F Shirini, Y Bayat… - Journal of Molecular …, 2023 - Elsevier
In this article a simple method is reported for the promotion of the synthesis of imidazo [1, 2-
a] pyrimidine-3-carbonitriles and 1, 2, 4-triazolo [4, 3-a] pyrimidines derivatives via three …

Iodine-Promoted C–H Bond Amination Reaction for the Synthesis of Fused Tricyclic Heteroarenes

RE Crittell, R Nakiwala, MJ Lavenue… - The Journal of …, 2024 - ACS Publications
Fused heterocyclic scaffolds, such as benzimidazoles or larger ring systems containing a
benzimidazole fragment, are frequently encountered in pharmaceutical compounds and …

Antiparasitic Activity of Fluorophenyl-Substituted Pyrimido[1,2-a]benzimidazoles

ISA Nasr, WS Koko, TA Khan, R Schobert, B Biersack - Biomedicines, 2023 - mdpi.com
A series of fourteen pyrimido [1, 2-a] benzimidazole compounds was prepared by
straightforward heterocyclic chemistry and oxidation methods. The new …