The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

Paracrine factors released by stem cells of mesenchymal origin and their effects in cardiovascular disease: a systematic review of pre-clinical studies

NS Mabotuwana, L Rech, J Lim, SA Hardy… - Stem cell reviews and …, 2022 - Springer
Mesenchymal stem cell (MSC) therapy has gained significant traction in the context of
cardiovascular repair, and have been proposed to exert their regenerative effects via the …

Adipokines at the crossroads of obesity and mesenchymal stem cell therapy

DV Pham, TK Nguyen, PH Park - Experimental & Molecular Medicine, 2023 - nature.com
Mesenchymal stem cell (MSC) therapy is an emerging treatment strategy to counteract
metabolic syndromes, including obesity and its comorbid disorders. However, its …

Translating MSC therapy in the age of obesity

L Boland, LM Bitterlich, AE Hogan, JA Ankrum… - Frontiers in …, 2022 - frontiersin.org
Mesenchymal stromal cell (MSC) therapy has seen increased attention as a possible option
to treat a number of inflammatory conditions including COVID-19 acute respiratory distress …

Adipokines as novel biomarkers of cardio-metabolic disorders

X Su, D Peng - Clinica Chimica Acta, 2020 - Elsevier
Obesity, defined as having a body mass index (BMI) greater than 30 kg/m 2, has been
verified to be associated with several health problems which are always grouped as …

Pathology of metabolically-related dyslipidemia

X Su, X Chen, B Wang - Clinica Chimica Acta, 2021 - Elsevier
It is well established that overweight/obesity is closely associated with multiple health
problems. Among these, dyslipidemia is the most important and main driving force behind …

Corneal mesenchymal stromal cells are directly antiangiogenic via PEDF and sFLT-1

M Eslani, I Putra, X Shen, J Hamouie… - … & visual science, 2017 - iovs.arvojournals.org
Methods: Co-MSCs were extracted from human cadaver, and wild-type (C57BL/6J) and
SERPINF1−/− mice corneas. The MSC secretome was collected in a serum-free medium …

Mesenchymal stem cells in radiation-induced lung injury: From mechanisms to therapeutic potential

G Hou, J Li, W Liu, J Wei, Y Xin, X Jiang - Frontiers in Cell and …, 2022 - frontiersin.org
Radiotherapy (RT) is an effective treatment option for multiple thoracic malignant tumors,
including lung cancers, thymic cancers, and tracheal cancers. Radiation-induced lung injury …

Anti-fibrotic mechanisms of exogenously-expanded mesenchymal stromal cells for fibrotic diseases

JS Rockel, R Rabani, S Viswanathan - Seminars in cell & developmental …, 2020 - Elsevier
Most chronic diseases involving inflammation have a fibrotic component that involves
remodeling and excess accumulation of extracellular matrix components. Left unchecked …

Novel insights into the pathological mechanisms of metabolic related dyslipidemia

X Su, Y Cheng, G Zhang, B Wang - Molecular Biology Reports, 2021 - Springer
Due to the technological advances, it has been well-established that obesity is strongly
correlated with various health problems. Among these problems, dyslipidemia is one of the …