Histone modifications in Alzheimer's disease

DA Santana, MAC Smith, ES Chen - Genes, 2023 - mdpi.com
Since Late-onset Alzheimer's disease (LOAD) derives from a combination of genetic variants
and environmental factors, epigenetic modifications have been predicted to play a role in the …

[HTML][HTML] Uncoupling proteins as a therapeutic target for the development of new era drugs against neurodegenerative disorder

R Kumar, T Amruthanjali, S Singothu, SB Singh… - Biomedicine & …, 2022 - Elsevier
Mitochondrial uncoupling proteins (UCP) are a part of the large family of mitochondrial
solute carriers (SLC25s), concentrated in the inner mitochondrial membrane that carries …

Complicated role of exercise in modulating memory: a discussion of the mechanisms involved

M Ebrahimnejad, P Azizi, V Alipour… - Neurochemical …, 2022 - Springer
Evidence has shown the beneficial effects of exercise on learning and memory. However,
many studies have reported controversial results, indicating that exercise can impair …

Fecal microbiota transplantation and short-chain fatty acids improve learning and memory in fluorosis mice by BDNF-PI3K/AKT pathway

T Zhao, J Lv, M Peng, J Mi, S Zhang, J Liu… - Chemico-Biological …, 2024 - Elsevier
Fluoride, an environmental toxicant, not only arouses intestinal microbiota dysbiosis, but
also causes neuronal apoptosis and a decline in learning and memory ability. The purpose …

Duodenal metabolic profile changes in heat-stressed broilers

JS Dridi, ES Greene, CW Maynard, G Brugaletta… - Animals, 2022 - mdpi.com
Simple Summary Heat stress (HS) represents an environmental and socio-economic burden
to the poultry industry worldwide. However, the underpinning mechanisms for HS responses …

Sodium butyrate exerts a neuroprotective effect in rats with acute carbon monoxide poisoning by activating autophagy through the mTOR signaling pathway

J Wen, Q Xu, J Li, X Shen, X Zhou, J Huang, S Liu - Scientific Reports, 2024 - nature.com
Acute carbon monoxide (CO) poisoning is a prevalent type of poisoning that causes
significant harm globally. Delayed encephalopathy after acute carbon monoxide poisoning …

Acetylome analyses provide novel insights into the effects of chronic intermittent hypoxia on hippocampus-dependent cognitive impairment

F Liu, W Yan, C Chen, Y Zeng, Y Kong, X He… - Frontiers in Molecular …, 2024 - frontiersin.org
Introduction Chronic intermittent hypoxia (CIH) can negatively affect hippocampal function
through various molecular mechanisms. Protein acetylation, a frequently occurring …

[HTML][HTML] Comprehensive prospects of high-altitude cognitive dysfunction and the positive role of traditional Chinese medicine

L Yang, Y Li, T Yue, Z Zhang, Y Hu, J Hou - … Research-Modern Chinese …, 2023 - Elsevier
Introduction High altitude cognitive dysfunction (HACD) is a type of cognitive impairment that
is associated with exposure to high-altitude environments. This condition is characterized by …

Introduction to high altitude and hypoxia

P Sharma, P Pandey, P Kumari, NK Sharma - High Altitude Sickness …, 2022 - Springer
Climbing to a high altitude causes breathing to shorten, which reduces the amount of
oxygen in the tissues and causes hypoxia. High altitude sickness is a medical illness with …

Elucidating a Role for Glycogen Synthase Kinase-3 in the Regulation of Neuronal Oscillatory Function: Relevance to Learning and Memory

A Albeely - 2022 - atrium.lib.uoguelph.ca
Aberrant activity of the protein glycogen synthase kinase-3β (GSK-3β) has been implicated
in disorders of cognitive dysfunction, such as Alzheimer's Disease and schizophrenia …