GPCRs are optimal regulators of complex biological systems and orchestrate the interface between health and disease
H Leysen, D Walter, B Christiaenssen… - International journal of …, 2021 - mdpi.com
GPCRs arguably represent the most effective current therapeutic targets for a plethora of
diseases. GPCRs also possess a pivotal role in the regulation of the physiological balance …
diseases. GPCRs also possess a pivotal role in the regulation of the physiological balance …
[HTML][HTML] Mitochondria under the spotlight: On the implications of mitochondrial dysfunction and its connectivity to neuropsychiatric disorders
Neuropsychiatric disorders (NPDs) such as bipolar disorder (BD), schizophrenia (SZ) and
mood disorder (MD) are hard to manage due to overlapping symptoms and lack of …
mood disorder (MD) are hard to manage due to overlapping symptoms and lack of …
Post-translational modification analysis of VDAC1 in ALS-SOD1 model cells reveals specific asparagine and glutamine deamidation
MGG Pittalà, S Reina, SAM Cubisino, A Cucina… - Antioxidants, 2020 - mdpi.com
Mitochondria from affected tissues of amyotrophic lateral sclerosis (ALS) patients show
morphological and biochemical abnormalities. Mitochondrial dysfunction causes oxidative …
morphological and biochemical abnormalities. Mitochondrial dysfunction causes oxidative …
Novel biallelic nonsense mutation in IGHMBP2 gene linked to neuropathy (CMT2S): A comprehensive clinical, genetic and bioinformatic analysis of a Turkish patient …
Background Spinal muscular atrophy with respiratory distress type 1 (SMARD1) and Charcot-
Marie-Tooth type 2S (CMT2S) typically present before age 10. Genetic factors account for up …
Marie-Tooth type 2S (CMT2S) typically present before age 10. Genetic factors account for up …
A panoramic view of proteomics and multiomics in precision health
Health is often qualitatively defined as a status free from disease and its quantitative
definition requires finding the boundary separating health from pathological conditions …
definition requires finding the boundary separating health from pathological conditions …
Modeling Neural Circuits in Parkinson's Disease
G Ameen, B Osama - Handbook of Neurodegenerative Disorders, 2023 - Springer
Parkinson's disease is one of the most customary neurodegenerative defects in this age. A
lot of motor symptoms appear in the patient as well as other non-motor symptoms …
lot of motor symptoms appear in the patient as well as other non-motor symptoms …
Identification of Novel Genetic Biomarkers Linked to the Prodromal Stage of Parkinson's Disease (PD) Patients
MT Badawy - 2025 - fount.aucegypt.edu
Abstract Background and Objective: The early diagnosis of neurodegenerative diseases,
such as Parkinson's disease (PD), is particularly challenging because symptoms appear …
such as Parkinson's disease (PD), is particularly challenging because symptoms appear …
Modeling Neural Circuits in ParkinsonTs
G Ameen, B Osama - Handbook of Neurodegenerative Disorders, 2024 - Springer
Parkinson's disease is one of the most customary neurodegenerative defects in this age. A
lot of motor symptoms appear in the patient as well as other non-motor symptoms …
lot of motor symptoms appear in the patient as well as other non-motor symptoms …