Psychiatric and substance use disorders inflict major public health burdens worldwide. Their
widespread burden is compounded by a dearth of effective treatments, underscoring a dire …

Organic cation transporters (OCTs) facilitate the translocation of catecholamines, drugs and
xenobiotics across the plasma membrane in various tissues throughout the human body …

Objective To review the literature on the neuropharmacology of synthetic cathinones.
Methods A comprehensive literature search was carried out across multiple databases …

Impaired function of organic cation transporter 1 (OCT1) in hepatocellular carcinoma (HCC)
has been associated with unsatisfactory response to sorafenib. However, some patients …

Many drugs have chiral centers and are therapeutically applied as racemates. Thus, the
stereoselectivity in their interactions with membrane transporters needs to be addressed …

HT clearance, commonly mediated by transporters in the uptake-1 and uptake-2 families,
has been linked to 5-HT 1B receptor's action on behaviors. Since no specific transporters …

Methylenedioxymethamphetamine (MDMA,'ecstasy') is re‐emerging in clinical settings as a
candidate for the treatment of specific neuropsychiatric disorders (eg post‐traumatic stress …

Plasma membrane monoamine transporter (PMAT, Slc29a4) transports monoamine
neurotransmitters, including dopamine and serotonin, faster than more studied monoamine …

Organic cation transporters (OCTs) are membrane proteins that take up monoamines,
cationic drugs and xenobiotics. We previously reported novel missense mutations of organic …

3, 4-Methylenedioxymethamphetamine (MDMA,-ecstasy-is re-emerging in clinical settings
as a candidate for the treatment of specific psychiatric disorders (eg post-traumatic stress …