Transformed cells must acquire specific characteristics to be malignant. Weinberg and
Hanahan characterize these characteristics as cancer hallmarks. Though these features are …

The FBXW7 (F-box with 7 tandem WD40) protein encoded by the gene FBXW7 is one of the
crucial components of ubiquitin ligase called Skp1-Cullin1-F-box (SCF) complex that aids in …

Formononetin, an isoflavone, is extracted from various medicinal plants and herbs, including
the red clover (Trifolium pratense) and Chinese medicinal plant Astragalus membranaceus …

HPV-DNA integration into cellular chromatin is usually a necessary event in the
pathogenesis of HPV-related cancer; however, the mechanism of integration has not been …

Innate immunity comprises several inflammation-related modulatory pathways which receive
signals from an array of membrane-bound and cytoplasmic pattern recognition receptors …

High-risk types of human papillomavirus (HPV) are the causative agents of virtually all cases
of cervical cancer and a significant proportion of other anogenital cancers, as well as both …

Viruses are the causative agents of 10%–15% of human cancers worldwide. The most
common outcome for virus-induced reprogramming is genomic instability, including …

High risk strains of human papillomavirus (HPV), such as HPV 16, cause human cervical
carcinoma. The E6 protein of HPV 16 mediates the rapid degradation of p53, although this is …

Colon cancer (CC) is one of the most common and deadly cancers worldwide. Oncologists
are facing challenges such as development of drug resistance and lack of suitable drug …

High risk strains of human papillomavirus (HPV), such as HPV 16, cause human cervical
carcinoma. The E6 protein of HPV 16 mediates the rapid degradation of the tumor …