Abstract The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private–public
partnership between the UK Biobank (UKB) and eight biopharmaceutical companies that …

A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

Age-related macular degeneration (AMD) is a common cause of blindness in older
individuals. To accelerate the understanding of AMD biology and help design new …

Corneal transplantation or keratoplasty has developed rapidly in the past 10 years.
Penetrating keratoplasty, a procedure consisting of full-thickness replacement of the cornea …

As the age of the population increases in many nations, age‐related degenerative diseases
pose significant socioeconomic challenges. One of the key degenerative diseases that …

Age-related macular degeneration (AMD) is the most common cause of blindness among
the elderly in the developed world. While treatment is effective for the neovascular or “wet” …

To define the role of rare variants in advanced age-related macular degeneration (AMD)
risk, we sequenced the exons of 681 genes within all reported AMD loci and related …

Age-related macular degeneration is a major cause of blindness worldwide. With ageing
populations in many countries, more than 20% might have the disorder. Advanced age …

There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

Age-related macular degeneration (AMD) is a multifactorial disease influenced by a
combination of environmental factors and genetic variants. Genomic studies have been …