Heat-shock proteins are upregulated in cancer and protect several client proteins from
degradation. Therefore, they contribute to tumorigenesis and cancer metastasis by reducing …

Background Urothelial carcinoma (UC) is a common malignancy with significant associated
mortality. Recent clinical trials suggest an emerging role for HER2-targeted therapy. Testing …

Non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease which has an
unpredictable risk of progression to muscle-invasive bladder cancer (MIBC). The selection of …

Overexpression of Epidermal Growth Factor Receptor (EGFR) and HER-2 in Bladder Carcinoma
and Its Association with Patients’ Clinical Features - PMC Back to Top Skip to main content NIH …

Transitional cell carcinoma (TCC) is the most commonly diagnosed neoplasm in the urinary
bladder. Distant metastases to the regional lymph nodes, lungs, abdominal organs or bones …

Pathological staging and grading are crucial for risk assessment in non-muscle-invasive
bladder cancer (NMIBC). Molecular grading might support pathological evaluation and …

Purpose The aim of this study was to evaluate the overexpression of human epidermal
growth factor receptor 2 (HER2) in patients with bladder cancer (BCa) and to assess its …

Although human epidermal growth factor receptor 2 (HER2) plays a prognostic and
predictive role in breast and gastric cancer, its function in bladder cancer (BC) is still …

Studying bladder cancer molecular biology revealed the presence of genetic alterations. So,
detection of molecular biomarkers that help in monitoring the disease, evaluating the …

Simple Summary Some non-pathogenic viruses that do not cause serious illness in humans
can efficiently target and kill cancer cells and may be considered candidates for cancer …