Pathophysiology of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

V Manne, P Handa, KV Kowdley - Clinics in liver disease, 2018 - liver.theclinics.com
The pathophysiology of NAFL and NASH is complex and numerous intermediaries are
involved. Each year brings new and exciting developments as pieces of the …

[HTML][HTML] Imaging biomarkers of NAFLD, NASH, and fibrosis

V Ajmera, R Loomba - Molecular metabolism, 2021 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) is a clinicopathologic entity that
requires a liver biopsy assessment to diagnose the progressive form of NAFLD called non …

[PDF][PDF] Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of …

G Garcia‐Tsao, JG Abraldes, A Berzigotti… - Hepatology, 2017 - Wiley Online Library
This guidance provides a data-supported approach to risk stratification, diagnosis, and
management of patients with cirrhosis and portal hypertension (PH). A guidance document …

Randomised clinical trial: semaglutide versus placebo reduced liver steatosis but not liver stiffness in subjects with non‐alcoholic fatty liver disease assessed by …

A Flint, G Andersen, P Hockings… - Alimentary …, 2021 - Wiley Online Library
Background Glucagon‐like peptide‐1 receptor agonists may be a treatment option in
patients with non‐alcoholic fatty liver disease (NAFLD). Aims To investigate the effects of …

Advances in non-invasive assessment of hepatic fibrosis

R Loomba, LA Adams - Gut, 2020 - gut.bmj.com
Liver fibrosis should be assessed in all individuals with chronic liver disease as it predicts
the risk of future liver-related morbidity and thus need for treatment, monitoring and …

[HTML][HTML] Noninvasive evaluation of nonalcoholic fatty liver disease: Current evidence and practice

JH Zhou, JJ Cai, ZG She, HL Li - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
With the increasing number of individuals with diabetes and obesity, nonalcoholic fatty liver
disease (NAFLD) is becoming increasingly prevalent, affecting one-quarter of adults …

[HTML][HTML] KASL clinical practice guidelines: management of nonalcoholic fatty liver disease

SH Kang, HW Lee, JJ Yoo, Y Cho, SU Kim… - Clinical and …, 2021 - ncbi.nlm.nih.gov
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing rapidly worldwide
as the obese and diabetic populations increase, and it has been estimated to be 20–30% in …

Quantitative elastography methods in liver disease: current evidence and future directions

P Kennedy, M Wagner, L Castéra, CW Hong… - Radiology, 2018 - pubs.rsna.org
Chronic liver diseases often result in the development of liver fibrosis and ultimately,
cirrhosis. Treatment strategies and prognosis differ greatly depending on the severity of liver …

Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: the “Anticipate” study

JG Abraldes, C Bureau, H Stefanescu, S Augustin… - Hepatology, 2016 - journals.lww.com
In patients with compensated advanced chronic liver disease (cACLD), the presence of
clinically significant portal hypertension (CSPH) and varices needing treatment (VNT) bears …

MRI and MRE for non-invasive quantitative assessment of hepatic steatosis and fibrosis in NAFLD and NASH: clinical trials to clinical practice

PS Dulai, CB Sirlin, R Loomba - Journal of hepatology, 2016 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) represents one of the most common causes of
chronic liver disease, and its prevalence is rising worldwide. The occurrence of non …