Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

Chronic hepatitis B virus (HBV) infection remains to be a serious threat to public health and
is associated with many liver diseases including chronic hepatitis B (CHB), liver cirrhosis …

Hepatitis B virus (HBV) produces circular RNA (circRNA), whose functions have not yet been
clearly elucidated. In this study, a novel circRNA HBV_circ_1 produced by HBV was …

Regulation of alternative splicing is one of the most efficient mechanisms to enlarge the
proteomic diversity in eukaryotic organisms. Many viruses hijack the splicing machinery …

During hepatitis B virus (HBV) replication, spliced HBV genomes and splice-generated
proteins have been widely described, however, their biological and clinical significance …

Hepatitis B spliced protein (HBSP) is known to associate with viral persistence and
pathogenesis; however, its biological and clinical significance remains poorly defined …

Background & Aims Hepatitis B virus (HBV) RNA can undergo alternative splicing, but the
relevance of this post-transcriptional regulation remains elusive. The mechanism of HBV …

Global cancer incidence and mortality are on the rise. Although cancer is fundamentally a
non-communicable disease, a large number of cancers are known to have a viral aetiology …

Purpose Trans-acting splicing factors (SF) shape the eukaryotic transcriptome by regulating
alternative splicing (AS). This process is recurrently modulated in liver cancer suggesting its …

Hepatitis B virus (HBV) infection has a multi-dimensional effect on the host, which not only
alters the dynamics of immune response but also persists in the hepatocytes to predispose …