The evolution of the hallmarks of aging

M Lemoine - Frontiers in Genetics, 2021 - frontiersin.org
The evolutionary theory of aging has set the foundations for a comprehensive understanding
of aging. The biology of aging has listed and described the “hallmarks of aging,” ie, cellular …

Mobilizing molluscan models and genomes in biology

A Davison, M Neiman - Philosophical Transactions of the …, 2021 - royalsocietypublishing.org
Molluscs are among the most ancient, diverse, and important of all animal taxa. Even so, no
individual mollusc species has emerged as a broadly applied model system in biology. We …

A pan‐metazoan concept for adult stem cells: the wobbling Penrose landscape

B Rinkevich, L Ballarin, P Martinez… - Biological …, 2022 - Wiley Online Library
Adult stem cells (ASCs) in vertebrates and model invertebrates (eg Drosophila
melanogaster) are typically long‐lived, lineage‐restricted, clonogenic and quiescent cells …

[HTML][HTML] A genetic and microscopy toolkit for manipulating and monitoring regeneration in Macrostomum lignano

RN Hall, H Li, C Chai, S Vermeulen, RR Bigasin… - Cell Reports, 2024 - cell.com
Live imaging of regenerative processes can reveal how animals restore their bodies after
injury through a cascade of dynamic cellular events. Here, we present a comprehensive …

Influence of temperature on development, reproduction and regeneration in the flatworm model organism, Macrostomum lignano

J Wudarski, K Ustyantsev, L Glazenburg, E Berezikov - Zoological letters, 2019 - Springer
Background The free-living marine flatworm Macrostomum lignano is a powerful model
organism for use in studying mechanisms of regeneration and stem cell regulation due to its …

[HTML][HTML] Macrostomum lignano Complements the Portfolio of Simple Animal Models Used for Marine Toxicological Studies

Y Ma, T Roeder - International Journal of Molecular Sciences, 2024 - mdpi.com
Macrostomum lignano is gaining increasing recognition as a model organism for
toxicological studies in marine ecosystems and expands the range of simple animal models …

Contribution of soft-bodied meiofaunal taxa to Italian marine biodiversity

M Curini-Galletti, T Artois, M Di Domenico… - The European …, 2020 - Taylor & Francis
Meiofauna includes an astonishing diversity of organisms, whose census is far from being
complete. Most classic ecological studies have focused on hard-bodied Ecdysozoan taxa …

Articulating the “stem cell niche” paradigm through the lens of non-model aquatic invertebrates

P Martinez, L Ballarin, AV Ereskovsky, E Gazave… - BMC biology, 2022 - Springer
Stem cells (SCs) in vertebrates typically reside in “stem cell niches”(SCNs), morphologically
restricted tissue microenvironments that are important for SC survival and proliferation …

[HTML][HTML] Genome-wide identification and characterization of long intergenic noncoding RNAs in the regenerative flatworm Macrostomum lignano

A Azlan, MA Halim, G Azzam - Genomics, 2020 - Elsevier
The free-living flatworm Macrostoma lignano (M. lignano) is an emerging model organism
for aging and regeneration research. Long intergenic non-coding RNAs (lincRNAs) have …

Novel protein from larval sponge cells, ilborin, is related to energy turnover and calcium binding and is conserved among marine invertebrates

I Borisenko, M Daugavet, A Ereskovsky… - Open …, 2022 - royalsocietypublishing.org
Sponges (phylum Porifera) are early-branching animals, whose outwardly simple body plan
is underlain by a complex genetic repertoire. The transition from a mobile larva to an …