Leigh syndrome is a mitochondrial disease characterized by neurodegeneration,
neuroinflammation, and early death. Mice lacking NDUFS4, a mitochondrial complex I …

The first formal consensus diagnostic criteria for myelin oligodendrocyte glycoprotein
antibody-associated disease (MOGAD) were recently proposed. Yet, the distinction of …

Tissue-resident immune cells, such as innate lymphoid cells, mediate protective or
detrimental immune responses at barrier surfaces. Upon activation by stromal or epithelial …

Abstract Cytokines, particularly IL-6, play a crucial role in modulating immune responses in
the central nervous system (CNS). Elevated IL-6 levels have been observed in …

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. It is characterized by a high incidence, high mortality rate, and poor …

Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease leading to
demyelination and axonal loss. Current treatments are immunomodulatory or …

Dendritic cells (DCs) are key regulators of adaptive immunity, guiding T helper (Th) cell
differentiation through antigen presentation, co-stimulation, and cytokine production …

Background: With the discovery of more and more drug–resistant bacterial strains, there is
an urgent need for safer and more effective alternative treatments. In this study, antibacterial …

Objective: Using network pharmacology and molecular docking technology to explore the
possible mechanism of Huangqi (Astragali radix)-Danggui (Angelicae sinensis radix) on the …

The multi-system, autoimmune disease systemic lupus erythematosus (SLE) often involves
the nervous system. Through largely unexplored mechanisms, patients develop cognitive …