Human embryonic stem cells have emerged as the prototypical source from which
cardiomyocytes can be derived for use in drug discovery and cell therapy. However, such …

Several in-vivo heart developmental models have been applied to decipher the cardiac
developmental patterning encompassing early, dorsal, cardiac and visceral mesoderm as …

We have successfully developed both spontaneous and inductive cardiomyocyte
differentiation of iPS cells reprogrammed from human foreskin fibroblasts. The …

The differentiation process of murine embryonic stem cells into cardiomyocytes was
investigated with a compliant microfluidic platform which allows for versatile cell seeding …

Abstract Bone morphogenetic protein 2 (BMP2) belongs to the transforming growth factor-β
superfamily and plays a critical role in regulating ovarian follicle function. Currently, the role …

With the intent to achieve the best modalities for myocardial cell therapy, different cell types
are being evaluated as potent sources for differentiation into cardiomyocytes. Embryonic …

Induced pluripotent stem cells (iPS) can differentiate into cardiomyocytes (CM) and
represent a promising form of cellular therapy for heart regeneration. However, residual …

Primordial follicles (PF) are formed when somatic cells differentiate into flattened
pregranulosa cells, invaginate into the oocyte nests and encircle individual oocytes. We …

Although previous studies showed that cardiomyocytes (CMs) can be generated from
human embryonic stem cells (hESCs), the protocols for cryopreservation of hESC-derived …

Human pluripotent stem cells (hPSCs) have arisen as a source of cells for biomedical
research due to their developmental potential. Stem cells possess the promise of providing …