Pyroptosis and its role in autoimmune disease: a potential therapeutic target

R You, X He, Z Zeng, Y Zhan, Y Xiao… - Frontiers in …, 2022 - frontiersin.org
Autoimmune diseases are a group of heterogeneous diseases with diverse clinical
manifestations that can be divided into systemic and organ-specific. The common etiology of …

Pharmacotherapy against oxidative stress in chronic kidney disease: Promising small molecule natural products targeting nrf2-ho-1 signaling

MJ Uddin, EH Kim, MA Hannan, H Ha - Antioxidants, 2021 - mdpi.com
The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease
has become a major health problem. Oxidative stress (OS) plays an important role in the …

Involvement of trained immunity during autoimmune responses

VP Mora, RA Loaiza, JA Soto, K Bohmwald… - Journal of …, 2023 - Elsevier
Recently, it has been described that innate immune cells such as monocytes, macrophages,
and natural killer cells can develop a non-specific immune response induced by different …

Potential of olive oil mill wastewater as a source of polyphenols for the treatment of skin disorders: a review

M Carrara, MT Kelly, F Roso, M Larroque… - Journal of Agricultural …, 2021 - ACS Publications
Current trends toward naturally occurring compounds of therapeutic interest have
contributed to an increasing number of studies on olive oil phenolics in the treatment of …

[HTML][HTML] Oleuropein: Methods for extraction, purifying and applying

DM Otero, FM Oliveira, A Lorini, BF Antunes… - Revista …, 2020 - SciELO Brasil
Oleuropein is one of the most abundant phenolic compounds present in olive leaves, and
many studies have shown that this compound has important biological properties (anti …

Ligstroside aglycon, an extra virgin olive oil secoiridoid, prevents inflammation by regulation of MAPKs, JAK/STAT, NF-κB, Nrf2/HO-1, and NLRP3 inflammasome …

ML Castejón, T Montoya, J Ortega-Vidal, J Altarejos… - Food & Function, 2022 - pubs.rsc.org
Ligstroside aglycon (LA) is one of the main polyphenols in extra virgin olive oil (EVOO);
nevertheless, it is scarcely investigated. The aim of this study was to evaluate the …

MX2: Identification and systematic mechanistic analysis of a novel immune-related biomarker for systemic lupus erythematosus

XW Meng, ZL Cheng, ZY Lu, YN Tan, XY Jia… - Frontiers in …, 2022 - frontiersin.org
Background Systemic lupus erythematosus (SLE) is an autoimmune disease that involves
multiple organs. However, the current SLE-related biomarkers still lack sufficient sensitivity …

Dexmedetomidine alleviates inflammation in neuropathic pain by suppressing NLRP3 via Nrf2 activation

W Shan, X Liao, Y Tang, J Liu - Experimental and …, 2021 - spandidos-publications.com
The aim of the present study was to investigate the mechanism by which dexmedetomidine
(DEX) alleviates neuropathic pain in a chronic constriction injury (CCI) model in rats. A CCI …

Dietary oleacein, a secoiridoid from extra virgin olive oil, prevents collagen-induced arthritis in mice

MÁ Rosillo, I Villegas, V Vázquez-Román… - Food & Function, 2024 - pubs.rsc.org
Olacein (OLA), one of the main secoiridoids derived from extra virgin olive oil (EVOO), has
been shown to modulate oxidative and inflammatory responses in various pathological …

Oleocanthal supplemented diet improves renal damage and endothelial dysfunction in pristane-induced systemic lupus erythematosus in mice

T Montoya, M Sánchez-Hidalgo, ML Castejón… - Food Research …, 2023 - Elsevier
Systemic lupus erythematosus (SLE) is a multiorgan disorder with a deregulated immune-
inflammatory response. Nutritional therapy has been considered a promising approach to …