Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Recently, boronic acid-containing macromolecules have been utilized in a number of
biomedical applications, 1 including use in dynamic covalent materials, dual thermo-and …

Boron-containing molecules have been extensively used for the purposes of chemical
sensing, biological probe development and drug discovery. Due to boron's empty p orbital, it …

College, Quincy, IL. His graduate work in physical organic chemistry under Richard L.
Schowen of the University of Kansas Chemistry Department culminated in a Ph. D. degree in …

Proteases form one of the largest and more important groups of enzymes. They selectively
catalyze the hydrolysis of peptide bonds and can be divided into four major classes …

Boron-containing organic compounds have found widespread use in synthetic organic
chemistry. More recently, boronic acid-containing polymers have proven valuable in a …

The behavior and significance of slow-binding enzyme inhibitors Page 211 THE BEHAVIOR
AND SIGNIFICANCE OF SLOW-BINDING ENZYME INHIBITORS By JOHN F. MORRISON …

Phosphate moieties bind frequently at N-termini of helices in proteins. It is shown that this
corresponds with an optimal interaction of the helix dipole and the charged phosphate. This …

Boronic acid compounds have been used, because of their unique structural features, for the
development of potent enzyme inhibitors, boron neutron capture agents for cancer therapy …

Following a brief overview of the terrestrial distribution of boron in rocks, soil, and water, the
history of the discovery, early utilization, and geologic origin of borate minerals is …