The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …

In classical theories of cerebellar cortex, high-dimensional sensorimotor representations are
used to separate neuronal activity patterns, improving associative learning and motor …

Quantal neurotransmitter release at excitatory synapses depends on glutamate import into
synaptic vesicles by vesicular glutamate transporters (VGLUTs). Of the three known …

Corelease of GABA and glycine by mixed neurons is a prevalent mode of inhibitory
transmission in the vertebrate hindbrain. However, little is known of the functional …

Unipolar brush cells (UBC) are small, glutamatergic neurons residing in the granular layer of
the cerebellar cortex and the granule cell domain of the cochlear nuclear complex. Recent …

The internal structure of the cerebellum reflects an intriguing paradox; its cytoarchitecture is
relatively simple and repeated throughout, yet the connections between its neurons are …

Analysis of the interplay between cell proliferation and death has been greatly advantaged
by the development of CNS slice preparations. In slices, interactions between neurons and …

Projections of glutamatergic somatosensory and auditory fibers to the cochlear nucleus (CN)
are mostly nonoverlapping: projections from the spinal trigeminal nucleus (Sp5) terminate …

Ever since the groundbreaking work of Ramon y Cajal, the cerebellar cortex has been
recognized as one of the most regularly structured and wired parts of the brain formed by a …

In this review, we briefly describe glutamate (Glu) metabolism and its specific transports and
receptors in the central nervous system (CNS). Thereafter, we focus on excitatory amino acid …