Deep learning for cellular image analysis

E Moen, D Bannon, T Kudo, W Graf, M Covert… - Nature …, 2019 - nature.com
Recent advances in computer vision and machine learning underpin a collection of
algorithms with an impressive ability to decipher the content of images. These deep learning …

[HTML][HTML] Software tools for 3D nuclei segmentation and quantitative analysis in multicellular aggregates

F Piccinini, T Balassa, A Carbonaro, A Diosdi… - Computational and …, 2020 - Elsevier
Today, we are fully immersed into the era of 3D biology. It has been extensively
demonstrated that 3D models:(a) better mimic the physiology of human tissues;(b) can …

[HTML][HTML] Number of necessary training examples for neural networks with different number of trainable parameters

TI Götz, S Göb, S Sawant, XF Erick, T Wittenberg… - Journal of Pathology …, 2022 - Elsevier
In this work, the network complexity should be reduced with a concomitant reduction in the
number of necessary training examples. The focus thus was on the dependence of proper …

Interstitial fibrosis and tubular atrophy measurement via hierarchical extractions of kidney and atrophy regions with deep learning method

Y Lai, X Liu, Y Wu, D Zhou, C Wang, D Niu, W Han… - Measurement, 2022 - Elsevier
Background and objective: Interstitial fibrosis and tubular atrophy (IFTA) are the most critical
characteristics of chronic kidney disease, and it is superior to glomerular pathology in …

Centroid calculation of the blastomere from 3D Z-Stack image data of a 2-cell mouse embryo

MM Trivedi, JK Mills - Biomedical Signal Processing and Control, 2020 - Elsevier
During cell surgery, cell manipulation tasks such as placement of cells, extraction of
organelles, blastomeres, or other structures from within a cell are essential. To enable these …

Multi-scale structural analysis of proteins by deep semantic segmentation

RR Eguchi, PS Huang - Bioinformatics, 2020 - academic.oup.com
Motivation Recent advances in computational methods have facilitated large-scale sampling
of protein structures, leading to breakthroughs in protein structural prediction and enabling …

Benchmarking of deep learning algorithms for 3D instance segmentation of confocal image datasets

A Kar, M Petit, Y Refahi, G Cerutti… - PLoS computational …, 2022 - journals.plos.org
Segmenting three-dimensional (3D) microscopy images is essential for understanding
phenomena like morphogenesis, cell division, cellular growth, and genetic expression …

[PDF][PDF] Assessment of deep learning algorithms for 3D instance segmentation of confocal image datasets

A Kar, M Petit, Y Refahi, G Cerutti, C Godin… - Bioinformatics, 2021 - researchgate.net
Segmenting three dimensional microscopy images is essential for understanding
phenomena like morphogenesis, cell division, cellular growth and genetic expression …

SATINN: An automated neural network-based classification of testicular sections allows for high-throughput histopathology of mouse mutants

R Yang, AM Stendahl, KA Vigh-Conrad, M Held… - …, 2022 - academic.oup.com
Motivation The mammalian testis is a complex organ with a cellular composition that
changes smoothly and cyclically in normal adults. While testis histology is already an …

The “computable egg”: Myth or useful concept?

K Biasuz, B Leggio, E Faure, P Lemaire - Current Opinion in Systems …, 2018 - Elsevier
Abstract In 1994, Lewis Wolpert wondered “Will the egg be computable? That is given a total
description of the fertilized egg–the total DNA sequence and the location of all proteins and …