Anticancer plants: A review of the active phytochemicals, applications in animal models, and regulatory aspects
The rising burden of cancer worldwide calls for an alternative treatment solution. Herbal
medicine provides a very feasible alternative to western medicine against cancer. This …
medicine provides a very feasible alternative to western medicine against cancer. This …
Triptolide and its derivatives as cancer therapies
P Noel, DD Von Hoff, AK Saluja, M Velagapudi… - Trends in …, 2019 - cell.com
Triptolide, a compound isolated from a Chinese medicinal herb, possesses potent antitumor,
immunosuppressive, and anti-inflammatory properties, but is clinically limited due to its poor …
immunosuppressive, and anti-inflammatory properties, but is clinically limited due to its poor …
Triptolide: progress on research in pharmacodynamics and toxicology
Abstract Ethnopharmacological relevance Tripterygium wilfordii Hook. f.(Tripterygium
wilfordii), also known as Huangteng and gelsemium elegan, is a traditional Chinese …
wilfordii), also known as Huangteng and gelsemium elegan, is a traditional Chinese …
Molecular understanding and modern application of traditional medicines: triumphs and trials
Traditional medicines provide fertile ground for modern drug development, but first they must
pass along a pathway of discovery, isolation, and mechanistic studies before eventual …
pass along a pathway of discovery, isolation, and mechanistic studies before eventual …
Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)
Plants in the genus Tripterygium, such as Tripterygium wilfordii Hook. f., have a long history
of use in traditional Chinese medicine. In recent years there has been considerable interest …
of use in traditional Chinese medicine. In recent years there has been considerable interest …
Drug repurposing for cancer therapy
Y Xia, M Sun, H Huang, WL Jin - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …
health. Despite significant advances in surgical, radiotherapeutic and immunological …
Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms
ZL Zhou, YX Yang, J Ding, YC Li, ZH Miao - Natural product reports, 2012 - pubs.rsc.org
Covering: 1972 to 2011 Triptolide, a principal bioactive ingredient of Tripterygium wilfordii
Hook F, has attracted extensive exploration due to its unique structure of a diterpenoid …
Hook F, has attracted extensive exploration due to its unique structure of a diterpenoid …
Celastrol: molecular targets of thunder god vine
A Salminen, M Lehtonen, T Paimela… - … and biophysical research …, 2010 - Elsevier
Celastrol, a quinone methide triterpene, is a pharmacologically active compound present in
Thunder God Vine root extracts used as a remedy of inflammatory and autoimmune …
Thunder God Vine root extracts used as a remedy of inflammatory and autoimmune …
[图书][B] Thin layer chromatography in phytochemistry
M Waksmundzka-Hajnos, J Sherma, T Kowalska - 2008 - taylorfrancis.com
Thin layer chromatography (TLC) is increasingly used in the fields of plant chemistry,
biochemistry, and molecular biology. Advantages such as speed, versatility, and low cost …
biochemistry, and molecular biology. Advantages such as speed, versatility, and low cost …
Anti-inflammatory effects of 27 selected terpenoid compounds tested through modulating Th1/Th2 cytokine secretion profiles using murine primary splenocytes
CM Ku, JY Lin - Food chemistry, 2013 - Elsevier
This study investigated 27 selected terpenoid compounds, including 8 monoterpenoids, 7
sesqui-terpenoids, 3 di-terpenoids, 8 tri-terpenoids, and 1 tetra-terpenoid, for their Th1/Th2 …
sesqui-terpenoids, 3 di-terpenoids, 8 tri-terpenoids, and 1 tetra-terpenoid, for their Th1/Th2 …