Mimicking the mammalian plasma membrane: An overview of lipid membrane models for biophysical studies

A Luchini, G Vitiello - Biomimetics, 2020 - mdpi.com
Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …

Global analysis of the yeast knockout phenome

G Turco, C Chang, RY Wang, G Kim, EH Stoops… - Science …, 2023 - science.org
Genome-wide phenotypic screens in the budding yeast Saccharomyces cerevisiae, enabled
by its knockout collection, have produced the largest, richest, and most systematic …

Combined Second Harmonic Generation and Fluorescence Analyses of the Structures and Dynamics of Molecules on Lipids Using Dual-Probes: A Review

Y Hou, J Li, B Li, Q Yuan, W Gan - Molecules, 2022 - mdpi.com
Revealing the structures and dynamic behaviors of molecules on lipids is crucial for
understanding the mechanism behind the biophysical processes, such as the preparation …

Phytochemical analysis, anti-inflammatory, antioxidant activity of Calotropis gigantea and its therapeutic applications

S Sivapalan, S Dharmalingam, V Venkatesan… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Herbal remedies can be used to treat a variety of chronic
inflammatory illnesses, like rheumatoid arthritis and leprosy. The plant Calotropis gigantea …

Violacein targets the cytoplasmic membrane of bacteria

ACG Cauz, GPB Carretero, GKV Saraiva… - ACS infectious …, 2019 - ACS Publications
Violacein is a tryptophan-derived purple pigment produced by environmental bacteria,
which displays multiple biological activities, including strong inhibition of Gram-positive …

Heterodyne-detected sum frequency generation spectroscopic study of weakly hydrogen-bonded water at charged lipid interfaces, revisited

Y Nojima, S Yamaguchi - The Journal of Physical Chemistry C, 2021 - ACS Publications
The presence/absence of weakly hydrogen-bonded water molecules buried in the
hydrophobic moiety of charged lipids at aqueous interfaces has been a matter of debate. We …

Ibuprofen in a lipid bilayer: Nanoscale spatial arrangement

AS Kashnik, DS Baranov, SA Dzuba - Membranes, 2022 - mdpi.com
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic
effects. Understanding the molecular mechanisms of drug interaction with cell membranes is …

Ibuprofen and the phosphatidylcholine bilayer: membrane water permeability in the presence and absence of cholesterol

M Wood, M Morales, E Miller, S Braziel, J Giancaspro… - Langmuir, 2021 - ACS Publications
The interactions between drugs and cell membranes can modulate the structural and
physical properties of membranes. The resultant perturbations of the membrane integrity …

Spatial Arrangement of the Drug Ibuprofen in a Model Membrane in the Presence of Lipid Rafts

AS Kashnik, DS Baranov, SA Dzuba - The Journal of Physical …, 2024 - ACS Publications
Many pharmaceutical drugs are known to interact with lipid membranes through nonspecific
molecular interactions, which affect their therapeutic effect. Ibuprofen is a nonsteroidal anti …

Spontaneous unbinding transition of nanoparticles adsorbing onto biomembranes: interplay of electrostatics and crowding

A Chaudhury, K Debnath, NR Jana, JK Basu - Nanoscale, 2024 - pubs.rsc.org
Cellular membranes are constantly bombarded with biomolecules and nanoscale particles,
and cell functionality depends on the fraction of the bound/internalized entities …