[HTML][HTML] Chemical constituents and biological activities of species of Justicia: a review

GM Corrêa, AFC Alcântara - Revista Brasileira de farmacognosia, 2012 - SciELO Brasil
The Acanthaceae family is an important source of therapeutic drugs, and the
ethnopharmacological knowledge of this family requires urgent documentation as several of …

Boldine ameliorates vascular oxidative stress and endothelial dysfunction: Therapeutic implication for hypertension and diabetes

YS Lau, WC Ling, D Murugan… - Journal of Cardiovascular …, 2015 - journals.lww.com
Epidemiological and clinical studies have demonstrated that a growing list of natural
products, as components of the daily diet or phytomedical preparations, are a rich source of …

Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance

LP Ren, SMH Chan, XY Zeng, DR Laybutt, TJ Iseli… - PloS one, 2012 - journals.plos.org
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been implicated in
hepatic steatosis and insulin resistance. The present study investigated their roles in the …

[HTML][HTML] Plant polyphenols Morin and Quercetin rescue nitric oxide production in diabetic mouse aorta through distinct pathways

K Taguchi, I Tano, N Kaneko, T Matsumoto… - Biomedicine & …, 2020 - Elsevier
Diabetic vascular complications are associated with endothelial dysfunction. Various plant-
derived polyphenols benefit cardiovascular function by protecting endothelial nitric oxide …

Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats

B Sharma, N Singh - Psychopharmacology, 2011 - Springer
Rationale Vascular dementia is the second leading cause of dementia, which is strongly
associated with diabetes. Diabetes and dementia have become a major public health …

Boldine protects endothelial function in hyperglycemia-induced oxidative stress through an antioxidant mechanism

YS Lau, XY Tian, Y Huang, D Murugan… - Biochemical …, 2013 - Elsevier
Increased oxidative stress is involved in the pathogenesis and progression of diabetes.
Antioxidants are therapeutically beneficial for oxidative stress-associated diseases. Boldine …

Pitavastatin and 4'-hydroxy-3'-methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia during experimental diabetes

B Sharma, N Singh - Current neurovascular research, 2010 - ingentaconnect.com
Diabetes has been found to increase the probability of vascular dementia in humans. We
have investigated the effect of 4'-hydroxy-3'-methoxyacetophenone (HMAP), a NADPH …

Flavonols in the prevention of diabetes-induced vascular dysfunction

CH Leo, OL Woodman - Journal of cardiovascular pharmacology, 2015 - journals.lww.com
As flavonols are present in fruits and vegetables, they are consumed in considerable
amounts in the diet. There is growing evidence that the well-recognized antioxidant, anti …

Ameliorative effect of astaxanthin on endothelial dysfunction in streptozotocin-induced diabetes in male rats

ZW Zhao, W Cai, YL Lin, QF Lin, Q Jiang… - …, 2011 - thieme-connect.com
The present study was designed to examine whether astaxanthin (ASX, 3, 3-dihydroxybeta,
beta-carotene-4, 4-dione, CAS 472-61-7), a dietary antioxidant carotenoid that is naturally …

Chronic NaHS treatment decreases oxidative stress and improves endothelial function in diabetic mice

HH Ng, GS Yildiz, JM Ku, AA Miller… - Diabetes and …, 2017 - journals.sagepub.com
Hydrogen sulphide (H2S) is endogenously produced in vascular tissue and has anti-oxidant
and vasoprotective properties. This study investigates whether chronic treatment using the …