This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Curcumin is a phytochemical achieved from the plant turmeric. It is extensively utilized for
the treatment of several types of diseases such as cancers. Nevertheless, its efficiency has …

Many lead compounds fail to reach clinical trials despite being potent because of low
bioavailability attributed to their insufficient solubility making solubility a primary and crucial …

Nanocarriers are defined as structures and devices that are constructed using
nanomaterials which add functionality to the encapsulants. Being small in size and having a …

Injectable long‐acting cabotegravir (CAB LA) is effective and safe for pre‐exposure HIV
prophylaxis. It is recently approved for clinical use in those at high risk of contracting HIV …

The poor healing associated with chronic wounds affects millions of people worldwide
through high mortality rates and associated costs. Chronic wounds present three main …

The use of drug nanocrystals in the drug formulation is increasing due to the large number of
poorly water-soluble drug compounds synthetized and due to the advantages brought by the …

Macrophages are essential immune cells and play a major role in the immune response as
pro-inflammatory or anti-inflammatory agents depending on their plasticity and functions …

Introduction Most drugs used in therapy have low water-solubility, a factor that could reduce
their dissolution rate and oral bioavailability, representing a challenge in pharmaceutical …

Long-acting injectable (LAIs) delivery systems sustain the drug therapeutic action in the
body, resulting in reduced dosage regimen, toxicity, and improved patient compliance. Lipid …