Pseudomonas aeruginosa is associated with several human infections, mainly related to
healthcare services. In the hospital, it is associated with resistance to several antibiotics …

Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

Bacteria assume distinct lifestyles during the planktonic and biofilm modes of growth.
Increased levels of the intracellular messenger c-di-GMP determine the transition from …

Conditions that sustain constant bacterial growth are seldom found in nature. Oligotrophic
environments and competition among microorganisms force bacteria to be able to adapt …

Iron serves as a signal in Pseudomonas aeruginosa biofilm development. We examined the
influence of mutations in known and putative iron acquisition-signaling genes on biofilm …

Pseudomonas aeruginosa causes chronic biofilm infections, and its ability to attach to
surfaces and other cells is important for biofilm formation and maintenance. Mutations in a …

For many years bacteria were considered primarily as autonomous unicellular organisms
with little capacity for collective behaviour. However, we now appreciate that bacterial cells …

Metabolites, substrates and substrate impurities may be toxic to cells by damaging biological
molecules, organelles, membranes or disrupting biological processes. Chemical stress is …

The sputum (mucus) layer of the cystic fibrosis (CF) lung is a complex substrate that provides
Pseudomonas aeruginosa with carbon and energy to support high-density growth during …

The σS (or RpoS) subunit of RNA polymerase is the master regulator of the general stress
response in Escherichia coli. While nearly absent in rapidly growing cells, σS is strongly …