Movement abnormalities of Parkinson's disease (PD) arise from disordered neural activity in
multiple interconnected brain structures. The planning and execution of movement requires …

The human motor cortex comprises a microcircuit of five interconnected layers with different
cell types. In this Review, we use a layer-specific and cell-specific approach to integrate …

Patients with Parkinson's disease (PD) exhibit multifaceted changes in neurophysiological
brain activity, hypothesized to represent a global cortical slowing effect. Using task-free …

Parkinson's disease (PD) is a progressive and debilitating brain disorder. Besides the
characteristic movement-related symptoms, the disease also causes decline in sensory and …

Parkinson's disease (PD) is marked by the death of neuromelanin-rich dopaminergic and
noradrenergic cells in the substantia nigra (SN) and the locus coeruleus (LC), respectively …

Objective Parkinson's disease (PD) affects the structural integrity and neurophysiological
signaling of the cortex. These alterations are related to the motor and cognitive symptoms of …

Background Research in healthy young adults shows that characteristic patterns of brain
activity define individual" brain-fingerprints" that are unique to each person. However …

Parkinson's disease (PD) is a multifaceted neurodegenerative disorder accompanied by
mild cognitive impairment (MCI) as a crucial nonmotor manifestation. Event-related …

Intracerebral recordings from movement disorders patients undergoing deep brain
stimulation have allowed the identification of pathophysiological patterns in oscillatory …

Parkinson's disease (PD) is associated with changes in neural activity in the sensorimotor
alpha and beta bands. Using magnetoencephalography (MEG), we investigated the role of …