Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

Mass spectrometry-based proteomics empowers deep profiling of proteome and protein
posttranslational modifications (PTMs) in Alzheimer's disease (AD). Here we review the …

Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Ginkgo biloba is an ancient plant species that is thought to provide a variety of health
benefits to living organisms and contains plenty of bioactive components, making it a …

The prevalence of multiple sclerosis (MS) and the age of affected patients are increasing
owing to increased longevity of the general population and the availability of effective …

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth
factors that plays a crucial role in the development of the nervous system while supporting …

Brain cells normally respond adaptively to oxidative stress or bioenergetic challenges,
resulting from ongoing activity in neuronal circuits. During aging and in neurodegenerative …

Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide.
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …

Neurotrophic factors comprise essential secreted proteins that have several functions in
neural and non-neural tissues, mediating the development, survival and maintenance of …

Neurodegenerative diseases are conventionally demarcated as disorders with selective loss
of neurons. Conventional as well as newer molecules have been tested but they offer just …