Considerations and caveats in combating ESKAPE pathogens against nosocomial infections

YX Ma, CY Wang, YY Li, J Li, QQ Wan… - Advanced …, 2020 - Wiley Online Library
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Review of the syntheses and activities of some sulfur-containing drugs

CT Barce Ferro, BF Dos Santos… - Current Organic …, 2020 - ingentaconnect.com
Background: Sulfur-containing compounds represent an important class of chemical
compounds due to their wide range of biological and pharmaceutical properties. Moreover …

Scalable selective electrochemical oxidation of sulfides to sulfoxides

ZH Fu, HD Tian, SF Ni, JS Wright, M Li, LR Wen… - Green …, 2022 - pubs.rsc.org
An electrochemical protocol for the selective oxidation of sulfides to sulfoxides has been
developed in which NaCl plays a dual role:(1) as an electrolyte for the electrochemical …

Cyclic sulfinamides

AV Dobrydnev, MV Popova… - The Chemical …, 2024 - Wiley Online Library
The literature on cyclic sulfinamides (put simply, sultims) published from 1989 to 2022 has
been summarized and reviewed. The information is divided into two sections: the analysis of …

Recent drug-repurposing-driven advances in the discovery of novel antibiotics

AK Konreddy, GU Rani, K Lee… - Current medicinal …, 2019 - ingentaconnect.com
Drug repurposing is a safe and successful pathway to speed up the novel drug discovery
and development processes compared with de novo drug discovery approaches. Drug …

Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE)

A AbdelKhalek, NS Abutaleb, H Mohammad… - PloS one, 2018 - journals.plos.org
Enterococci represent one of the microbial world's most challenging enigmas. Colonization
of the gastrointestinal tract (GIT) of high-risk/immunocompromised patients by enterococci …

Novel alkylated azoles as potent antifungals

SK Shrestha, A Garzan… - European Journal of …, 2017 - Elsevier
Fluconazole (FLC) is the drug of choice when it comes to treat fungal infections such as
invasive candidiasis in humans. However, the widespread use of FLC has resulted in the …

Ketone-and cyano-selenoesters to overcome efflux pump, quorum-sensing, and biofilm-mediated resistance

N Szemerédi, A Kincses, K Rehorova, L Hoang… - Antibiotics, 2020 - mdpi.com
The emergence of drug-resistant pathogens leads to a gradual decline in the efficacy of
many antibacterial agents, which poses a serious problem for proper therapy. Multidrug …

Identification of Ebsulfur analogues with broad‐spectrum antifungal activity

HX Ngo, SK Shrestha… - ChemMedChem, 2016 - Wiley Online Library
Invasive fungal infections are on the rise due to an increased population of critically ill
patients as a result of HIV infections, chemotherapies, and organ transplantations. Current …

Promising treatment strategies to combat Staphylococcus aureus biofilm infections: an updated review

PS Seethalakshmi, R Rajeev, GS Kiran, J Selvin - Biofouling, 2020 - Taylor & Francis
Staphylococcus aureus is a leading cause of nosocomial and community-acquired
infections. The formation of biofilm by this pathogen renders it resilient to antimicrobial …