A global federated real-world data and analytics platform for research

MB Palchuk, JW London, D Perez-Rey, ZJ Drebert… - JAMIA …, 2023 - academic.oup.com
Objective This article describes a scalable, performant, sustainable global network of
electronic health record data for biomedical and clinical research. Materials and Methods …

[HTML][HTML] Psychotropic drug repurposing for COVID-19: a systematic review and meta-analysis

G Fico, U Isayeva, M De Prisco, V Oliva, B Sole… - European …, 2023 - Elsevier
Several psychotropic drugs, including antidepressants (AD), mood stabilizers, and
antipsychotics (AP) have been suggested to have favorable effects in the treatment of …

Implications of adverse outcomes associated with antipsychotics in older patients with dementia: a 2011–2022 update

M Rogowska, M Thornton, B Creese, L Velayudhan… - Drugs & Aging, 2023 - Springer
Neuropsychiatric symptoms affect most patients with dementia over the course of the
disease. They include a wide variety of symptoms from apathy and depression to psychosis …

Rates of antipsychotic drug prescribing among people living with dementia during the COVID-19 pandemic

H Luo, WCY Lau, Y Chai, CO Torre, R Howard… - Jama …, 2023 - jamanetwork.com
Importance Concerns have been raised that the use of antipsychotic medication for people
living with dementia might have increased during the COVID-19 pandemic. Objective To …

Antipsychotic drug prescribing and mortality in people with dementia before and during the COVID-19 pandemic: a retrospective cohort study in Wales, UK

C Schnier, A McCarthy, DR Morales… - The Lancet Healthy …, 2023 - thelancet.com
Background Concerns have been raised that antipsychotic drug prescribing, which has
been associated with increased mortality in people with dementia, might have increased …

“I felt like I had been put on the shelf and forgotten about”–lasting lessons about the impact of COVID-19 on people affected by rarer dementias

E Harding, S Rossi-Harries, EV Gerritzen… - BMC geriatrics, 2023 - Springer
Background The public health measures imposed in many countries to contain the spread of
COVID-19 resulted in significant suspensions in the provision of support and care for people …

Aripiprazole as protector against COVID-19 mortality

C Loucera-Muñecas, M Canal-Rivero… - Scientific Reports, 2024 - nature.com
The relation of antipsychotics with severe Coronavirus Disease 19 (COVID-19) outcomes is
a matter of debate since the beginning of the pandemic. To date, controversial results have …

Adherence to Recommended Metabolic Monitoring of Children and Adolescents Taking Second-Generation Antipsychotics

S Sanyal, C Calarge, PJ Rowan… - Psychiatric …, 2024 - Am Psychiatric Assoc
Objective: Clinical guidelines recommend periodic monitoring for adverse metabolic effects
associated with second-generation antipsychotic medications. The authors sought to …

Psychotropic use for behavioral and psychological symptoms of dementia during the COVID-19 pandemic: a systematic review and meta-analysis

JM Yoon, E Kim, AM Trinkoff - BMC geriatrics, 2024 - Springer
During the COVID-19 pandemic, the provision of quality care for behavioral and
psychological symptoms in older adults with dementia may have been impeded due to …

Outpatient antipsychotic use and severe COVID-19: avoiding the impact of age in a real-world data study

S Pintos-Rodríguez, I Visos-Varela… - International Journal …, 2024 - academic.oup.com
Background The association between use of antipsychotics and COVID-19 outcomes is
inconsistent, which may be linked to use of these drugs in age-related diseases …