An overview of herbal products and secondary metabolites used for management of type two diabetes

A Ota, NP Ulrih - Frontiers in pharmacology, 2017 - frontiersin.org
Diabetes mellitus is a common effect of uncontrolled high blood sugar and it is associated
with long-term damage, dysfunction, and failure of various organs. In the adult population …

Diabetic cardiomyopathy: molecular mechanisms, detrimental effects of conventional treatment, and beneficial effects of natural therapy

B Parim, VV Sathibabu Uddandrao, G Saravanan - Heart Failure Reviews, 2019 - Springer
Diabetic complications are among the largely exigent health problems currently.
Cardiovascular complications, including diabetic cardiomyopathy (DCM), account for more …

[HTML][HTML] Sepsis-mediated renal dysfunction: pathophysiology, biomarkers and role of phytoconstituents in its management

A Balkrishna, S Sinha, A Kumar, V Arya… - Biomedicine & …, 2023 - Elsevier
Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …

Protective effect of natural products against Huntington's disease: an overview of scientific evidence and understanding their mechanism of action

PT Lum, M Sekar, SH Gan, SR Bonam… - ACS chemical …, 2021 - ACS Publications
Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of
adult life, followed by a gradual occurrence of characteristic psychiatric disturbances and …

[HTML][HTML] S-Allyl-L-Cysteine—A garlic bioactive: Physicochemical nature, mechanism, pharmacokinetics, and health promoting activities

N Rais, A Ved, R Ahmad, M Kumar, MD Barbhai… - Journal of Functional …, 2023 - Elsevier
Abstract S-allyl-L-cysteine (SAC) is a sulfur-containing substance found in aged garlic
extract (AGE), which has been observed to have numerous biological activities, including …

Natural Hydrogen Sulfide Donors from Allium sp. as a Nutraceutical Approach in Type 2 Diabetes Prevention and Therapy

S Melino, S Leo, V Toska Papajani - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (DM) is a socially relevant chronic disease with high prevalence
worldwide. DM may lead to several vascular, macrovascular, and microvascular …

Restorative potentiality of S-allylcysteine against diabetic nephropathy through attenuation of oxidative stress and inflammation in streptozotocin–nicotinamide …

VV Sathibabu Uddandrao, P Brahmanaidu… - European journal of …, 2019 - Springer
Aim In the present study, we evaluated the therapeutic potentiality of S-allylcysteine (SAC) in
streptozotocin (STZ)–nicotinamide (NAD)-induced diabetic nephropathy (DN) in …

S-allyl cysteine protects against lipopolysaccharide-induced acute kidney injury in the C57BL/6 mouse strain: Involvement of oxidative stress and inflammation

MR Khajevand-Khazaei, S Azimi, L Sedighnejad… - International …, 2019 - Elsevier
Sepsis is a serious and life-threatening medical condition with a higher rate of patients'
morbidity and mortality and with complications such as acute kidney injury (AKI). S-allyl …

Anti-cancer activities of S-allylmercaptocysteine from aged garlic

LV Yi, SO Kwok-Fai, W Nai-Kei, X Jia - Chinese journal of natural medicines, 2019 - Elsevier
While most types of malignancies remain recalcitrant to treatment, application of natural
products or their analogs in daily life has offered some hopes as an effective prophylaxis …

Obesity-alleviating potential of asiatic acid and its effects on ACC1, UCP2, and CPT1 mRNA expression in high fat diet-induced obese Sprague–Dawley rats

P Rameshreddy, VVS Uddandrao… - Molecular and cellular …, 2018 - Springer
The present study evaluated the effects of asiatic acid (AA), a pentacyclic triterpenoid from
Centella asiatica on lipid metabolism parameters in a rat model of obesity induced using a …